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Treatment of Tinnitus with Intratympanic Injection of Dexamethasone Versus Oral Drugs

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Abstract

Tinnitus is a symptom of cochlear dysfunction, which can disturb the patient emotionally and physically. As anxiety and tinnitus persist concurrently, certain benzodiazepines have been administered as possible tinnitus treatment options. In addition to pharmacological medications, certain studies have looked at the use of vitamins to treat tinnitus. Intratympanic steroids have been successfully used in various studies as well, for the treatment of tinnitus. A clinical based interventional study was taken up among the patients visiting the ENT OPD of a State Medical College and Hospital. 160 subjects were included in the study by convenient sampling method, taking the inclusion and the exclusion criteria into consideration. Out of them, 80 subjects were given an intratympanic injection of dexamethasone and rest 80 were given oral drugs like alprazolam and vitamin B complex. Among the patients who were treated with intratympanic dexamethasone, significant improvement was seen in 36 of them, with a p value of 0.00 as compared to those who were given oral drugs, in which only 10 showed improvement, with a p value of 0.32. The improvement of the symptoms is significantly related with the duration of the symptoms in our study. Patients presenting with severe SNHL was the commonest presentation but had the least improvement (29.6%). Patients presenting within one year of occurrence of the symptoms had maximum improvement. Intratympanic dexamethasone can be considered as a good alternative for improvement of symptoms of tinnitus.

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The authors have no financial or proprietary interests in any material discussed in this article.

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Authors and Affiliations

  1. Nilratan Sircar Medical College and Hospital, Kolkata, India

    Arpita Mohanty & Biswajit Sikder

  2. Bankura Sammilani Medical College and Hospital, Bankura, India

    Monoj Mukherjee

  3. IPGME&R and SSKM Hospital, Kolkata, India

    Siddhartha Kumar Das

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  1. Arpita Mohanty
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  2. Monoj Mukherjee
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  3. Siddhartha Kumar Das
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  4. Biswajit Sikder
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Correspondence to Arpita Mohanty.

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Mohanty, A., Mukherjee, M., Das, S.K. et al. Treatment of Tinnitus with Intratympanic Injection of Dexamethasone Versus Oral Drugs. Indian J Otolaryngol Head Neck Surg 75, 2029–2034 (2023). https://doi.org/10.1007/s12070-023-03795-1

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  • DOI: https://doi.org/10.1007/s12070-023-03795-1

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