Skip to main content

Advertisement

SpringerLink
Log in

KTP 532 Laser Assisted Surgery for Oral Cavity Malignancy—A Retrospective Study

  • Original Article
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Aims and Objective

To determine the effectiveness of KTP 532 in surgically treating early and early advanced oral malignancy with no surgical reconstruction of primary site.

Materials and methods

It is a retrospective study of 67 cases operated between 2000 to 2013 including T1, T2 and Early T3 cases, approved by ethical committee. All the cases underwent Laser assisted excision of tumour with or without Neck Dissection or Adjuvant Radiotherapy. Age of the cases varied from 20 to 80 years with mean age of 49 years. 47 cases were males and 20 were females. 26 cases in the study had neck nodes clinically whereas 41 cases had N0 status. Neck dissection was done (SOND or MRND) in 61 cases. In 6 cases (N0) no neck dissection was done.

Results

61 cases had no loco-regional residual disease on their last follow up. Six cases had loco-regional recurrence within 6 months and salvage surgery was done. The overall mean survival was 81 months (92, 82 and 71 months in Stage I, II,III respectively). 3 year disease free survival rate was 91% as calculated using Kaplan- Meier Scale. In all these cases tumour was excised with KTP 532 laser and no reconstruction was done. Wound was allowed to heal with secondary intention.

Conclusion

Laser assisted excision of oral malignancy is an alternative to conventional treatment with more precision, less morbidity, shorter hospital stay and better functional outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Sulewski JG (2000) Historical survey of laser dentistry. Dent Clin North Am 44(4):717–752

    Article  CAS  PubMed  Google Scholar 

  2. Fornain C, Rocca JP, Merigo E, Meleti M, Manfredi M, Nammour S, Vescovi P (2012 Mar) Low energy KTP laser in oral soft tissues surgery: a 52 patients clinical study. Medicina oral, patologia oral y cirugia bucal. 17:e2872

  3. Gaspar L (1994) The use of high-power lasers in oral surgery. J Clin Laser Med Surg 12(5):281–285

    Article  CAS  PubMed  Google Scholar 

  4. Neukam FW, Stelzle F (2010 Jan) Laser tumor treatment in oral and maxillofacial surgery. Physics Procedia 1:5:91–100

  5. Strauss RA, Fallon SD (2004) Lasers in contemporary oral and maxillofacial surgery. Dent Clin North Am 48(4):861–888

    Article  PubMed  Google Scholar 

  6. Ishii J et al (2001) Clinical assessment of KTP laser surgery for tongue lesions—Comparison with CO 2 laser surgery. J Jpn Soc Laser Dentistry 12:10–15

    Article  Google Scholar 

  7. Lim B, Smith A, Chandu A Treatment of Oral Leukoplakia With Carbon Dioxide and Potassium-Titanyl-Phosphate Lasers: A Comparison.Journal of Oral and Maxillofacial Surgery. 68(3): p.597–601

  8. Basu MK, Frame JW, Rhys PH, Evans (1988) Wound healing following partial glossectomy using the CO 2 laser, diathermy and scalpel: a histological study in rats. J laryngology otology 102(4):322–327

    Article  CAS  Google Scholar 

  9. Lippert BM et al (2003) Wound healing after laser treatment of oral and oropharyngeal cancer. Lasers Med Sci 18(1):36–42

    Article  CAS  PubMed  Google Scholar 

  10. Singh GB, Tiwari M, Shukla HS, Pandey M (2009) Nd:YAG laser therapy of carcinoma lip (stage I squamous cell carcinoma): a retrospective evaluation. Indian J Otolaryngol Head Neck Surg 61(3):179–184

    Article  PubMed  PubMed Central  Google Scholar 

  11. Ihler C, Martin F, Wolff A, Matthias HA, Steiner C (2013) Enoral laser microsurgery for squamous cell carcinoma of the oral cavity. Head Neck 25(10):23365

    Google Scholar 

  12. Ishii J, Fujita K, Komori T (2002) Clinical assessment of laser monotherapy for squamous cell carcinoma of the mobile tongue. J Clin Laser Med Surg 20(2):57–61

    Article  PubMed  Google Scholar 

  13. Carew JF, Ward RF, LaBruna A, Torzilli PA, Schley WS (1998) Effects of scalpel, electrocautery, and CO2 and KTP lasers on wound healing in rat tongues. The Laryngoscope. Mar 1;108(3):373 – 80

  14. Kaya G, Yavuz GY, Sümbüllü MA, Dayı E (2012) A comparison of diode laser and Er: YAG lasers in the treatment of gingival melanin pigmentation. Oral surgery, oral medicine, oral pathology and oral radiology. Mar 1;113(3):293-9

  15. Kawczyk-Krupka A, Waśkowska J, Raczkowska-Siostrzonek A, Kościarz-Grzesiok A, Kwiatek S, Straszak D, Latos W, Koszowski R, Sieroń A (2012) Comparison of cryotherapy and photodynamic therapy in treatment of oral leukoplakia. Photodiagnosis and photodynamic therapy. Jun 1;9(2):148 – 55

  16. Montebugnoli L, Frini F, Gissi DB, Gabusi A, Cervellati F, Foschini MP, Marchetti C (2012 Jan) Histological and immunohistochemical evaluation of new epithelium after removal of oral leukoplakia with Nd: YAG laser treatment. Lasers in medical science. 27:205–2101

  17. Hegde R, Padhye A, Sumanth S, Jain AS, Thukral N (2013 Jun) Comparison of surgical stripping; erbium-doped: yttrium, aluminum, and garnet laser; and carbon dioxide laser techniques for gingival depigmentation: a clinical and histologic study. J Periodontol 84(6):738–748

  18. Vescovi P, Manfredi M, Merigo E, Meleti M, Fornaini C, Rocca JP, Nammour S (2010) Surgical approach with Er: YAG laser on osteonecrosis of the jaws (ONJ) in patients under bisphosphonate therapy (BPT). Lasers in medical science. Jan;25(1):101 – 13

  19. Misra N, Chittoria N, Umapathy D, Misra P (2013 Mar) Efficacy of diode laser in the management of oral lichen planus. Case Rep 15:2013:bcr2012007609

  20. Fornaini C, Raybaud H, Augros C, Rocca JP New clinical approach for use of Er: YAG laser in the surgical treatment of oral lichen planus: a report of two cases. Photomedicine and laser surgery. 2012 Apr 1;30(4):234-8

  21. Shafirstein G, Friedman A, Siegel E, Moreno M, Bäumler W, Fan CY, Morehead K, Vural E, Stack BC, Suen JY (2011) Using 5-aminolevulinic acid and pulsed dye laser for photodynamic treatment of oral leukoplakia. Archives of Otolaryngology–Head & Neck Surgery. Nov 1;137(11):1117-23

  22. Akbulut N, Kursun ES, Tumer MK, Kamburoglu K, Gulsen U (2013 Apr) Is the 810-nm diode laser the best choice in oral soft tissue therapy? Eur J dentistry 7(02):207–211

  23. Boj JR, Poirier C, Espasa E, Hernandez M, Espanya A (2009 May) Lower lip mucocele treated with an erbium laser. Pediatr Dent 15(3):249–252

  24. Asnaashari M, Mehdipour M, MoradiAbbasabadi F, Azari-Marhabi S (2015) Expedited removal of pyogenic granuloma by diode laser in a pediatric patient. J lasers Med Sci 6(1):40

    PubMed  PubMed Central  Google Scholar 

  25. López-Jornet P, Camacho-Alonso F (2013 Jan) Comparison of pain and swelling after removal of oral leukoplakia with CO2 laser and cold knife: a randomized clinical trial. Medicina oral, patologia oral y cirugia bucal. 18:e381

  26. Agha-Hosseini F, Moslemi E, Mirzaii-Dizgah I (2012) Comparative evaluation of low-level laser and CO2 laser in treatment of patients with oral lichen planus. International journal of oral and maxillofacial surgery. Oct 1;41(10):1265-9

  27. Jerjes W, Upile T, Hamdoon Z, Al-Khawalde M, Morcos M, Mosse CA, Hopper C (2012 Jan) CO2 laser of oral dysplasia: clinicopathological features of recurrence and malignant transformation. Lasers Med Sci 27(1):169–179

  28. Deppe H, Mücke T, Hohlweg-Majert B, Hauck W, Wagenpfeil S, Hölzle F (2012 Jan) Different CO2 laser vaporization protocols for the therapy of oral precancerous lesions and precancerous conditions: a 10-year follow-up. Lasers Med Sci 27(1):59–63

  29. Yang SW, Tsai CN, Lee YS, Chen TA (2011) Treatment outcome of dysplastic oral leukoplakia with carbon dioxide laser—emphasis on the factors affecting recurrence. Journal of Oral and Maxillofacial Surgery. Jun 1;69(6):e78-87

  30. Mozafari H, Farhadzadeh K, Rezaei F (2015) A study of the effects of CO2 laser therapy on oral lichen planus (OLP). J Appl Environ Biol Sci 5(9S):114–118

    Google Scholar 

  31. Yagüe García J, España Tost AJ, Berini Aytés L, Gay Escoda C (2009) Treatment of oral mucocele-scalpel versus CO2 laser. Medicina Oral, Patología Oral y Cirugia Bucal, vol. 14, num. 9, p. 469–474. 2009 Sep 1

  32. Monteiro LS, Mouzinho J, Azevedo A, Câmara MI, Martins MA, La Fuente JM (2012) Treatment of epulis fissuratum with carbon dioxide laser in a patient with antithrombotic medication. Braz Dent J 23:77–81

    Article  PubMed  Google Scholar 

  33. Lindenmüller IH, Noll P, Mameghani T, Walter C (2010 Aug) CO2 laser-assisted treatment of a giant pyogenic granuloma of the gingiva. Int J Dent hygiene 8(3):249–252

  34. Işeri U, Özçakır-Tomruk C, Gürsoy-Mert H (2009) Treatment of epulis fissuratum with CO2 laser and prosthetic rehabilitation in patients with vesiculobullous disease. Photomedicine and Laser Surgery. Aug 1;27(4):675 – 81

  35. Lai JB, Poon CY (2009) Treatment of ranula using carbon dioxide laser–Case series report. International journal of oral and maxillofacial surgery. Oct 1;38(10):1107-11

Download references

Author information

Authors and Affiliations

  1. Former Professor and Head of Department, Dept of Otorhinolaryngology- Head and Neck Surgery, Kasturba Medical College, Manipal, India

    Dipak Ranjan Nayak

  2. Assistant Professor, Dept of Otorhinolaryngology- Head and Neck Surgery, Government Medical College, Haldwani, India

    Pooja Dalakoti

  3. Professor , Dept of Otorhinolaryngology- Head and Neck Surgery, Kasturba Medical College, Manipal, India

    R. Balakrishnan & Kailesh Poojary

  4. Former Junior Resident, Dept of Otorhinolaryngology- Head and Neck Surgery, Kasturba Medical College, Manipal, India

    Uday Bhanu & Suraj Nair

Authors
  1. Dipak Ranjan Nayak
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Balakrishnan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Pooja Dalakoti
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Uday Bhanu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Suraj Nair
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Kailesh Poojary
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Pooja Dalakoti.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Electronic Supplementary Material

Below is the link to the electronic supplementary material.

Supplementary Material 1

Rights and permissions

Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nayak, D.R., Balakrishnan, R., Dalakoti, P. et al. KTP 532 Laser Assisted Surgery for Oral Cavity Malignancy—A Retrospective Study. Indian J Otolaryngol Head Neck Surg 75, 416–419 (2023). https://doi.org/10.1007/s12070-022-03214-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-022-03214-x

Search

Navigation