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Treatment of Childhood High-Grade Subglottic Stenosis (SGS) Through Laryngotracheoplasty (LTP) in a Tertiary Pediatric Center from 2013 to 2020

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Abstract

Laryngotracheal reconstruction is the most common and effective treatment in childhood subglottic stenosis (SGS). Our aim is to review the success rate of laryngotracheoplasty (LTP) in pediatric high grade SGS cases in our tertiary center. The retrospective review was conducted on children with high grade subglottic stenosis who had undergone laryngotracheoplasty over a 7-year period (2013–2020) in tertiary pediatric care. A total of 20 patients who had history of high grade SGS during the stipulated period were included. All of them had undergone LTP. Decannulation was considered the primary outcome measure of success. Surveillance bronchoscopy was performed one year post airway reconstruction to detect residual stenosis. From January 2013 to December 2020, 20 patients aged between 1 and 16 years old underwent LTP. Among them, 10 patients (50%) had Grade III SGS while 5 had Grade III SGS with glottis stenosis (25%). The remaining 5 (25%) had severe Grade IV stenosis. Decannulation was achieved in 14 patients overall (70%) including 1 with revision. These 14 patients who achieved decannulation included 7 out of the 10 patients (70%) with Grade III, 2 out of the 5 (40%) patients with Grade III with glottic involvement, and 4 out of the 5 patients (80%) with Grade IV SGS. Fifteen (80%) patients had double stage LTP while 5 patients had single stage LTP. The study suggests that LTP is a promising approach in the treatment of Complex SGS. Furthermore, pediatric SGS, which is inherently complicated, can be treated with LTP effectively.

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References

  1. Jefferson ND, Cohen AP, Rutter MJ (2016) Subglottic stenosis. Semin Pediatr Surg 25:138–143

    Article  Google Scholar 

  2. Redondo-Sedano J, Antón-Pacheco JL, Valverde RM, Díaz ML, Paredes CL, Guardia LM, Alelu RM, Huerta IJ, Gordo MIB, Fraile AG (2019) Laryngeal stenosis in children: types, grades and treatment strategies. J Pediatr Surg 54:1933–1937

    Article  Google Scholar 

  3. Cakir E, Atabek AA, Calim OF, Uzuner S, AlShadfan L, Yazan H, Ozturan O, Cakir FB (2020) Post-intubation subglottic stenosis in children: Analysis of clinical features and risk factors. Pediatr Int 62:386–389

    Article  Google Scholar 

  4. Maresh A, Preciado DA, O’Connell AP, Zalzal GH (2014) A comparative analysis of open surgery vs endoscopic balloon dilation for pediatric subglottic stenosis. JAMA Otolaryngol Neck Surg 140:901–905

    Article  Google Scholar 

  5. Oshri Wasserzug A (2016) DeRowe, subglottic stenosis: current concepts and recent advances. Int J Head Neck Surg 7:97–103

    Article  Google Scholar 

  6. Avelino MAG, da Silveira Botacin L, Coutinho MAC (2021) Treatment of complex laryngotracheal stenosis in childhood–experience of a tertiary University Hospital from 2016 to 2019. Ann Pediatr Surg 17:1–7

    Article  Google Scholar 

  7. Raman T, Chatterjee K, Alzghoul BN, Innabi AA, Tulunay O, Bartter T, Meena NK (2017) A bronchoscopic approach to benign subglottic stenosis. In: SAGE Open Med. Case Reports, 5: 2050313X17713151.

  8. Massie RJ, Robertson CF, Berkowitz RG (2000) Long-term outcome of surgically treated acquired subglottic stenosis in infancy. Pediatr Pulmonol 30:125–130

    Article  CAS  Google Scholar 

  9. Smith MM, Schweiger C, Manica D, Meotti CD, Eneas LV, Kuhl G, Marostica PJC (2012) Single-stage laryngotracheal reconstruction for the treatment of subglottic stenosis in children. Int Arch Otorhinolaryngol 16:217–221

    Article  Google Scholar 

  10. Rodríguez H, Cuestas G, Botto H, Cocciaglia A, Nieto M, Zanetta A (2013) Post-intubation subglottic stenosis in children Diagnosis, treatment and prevention of moderate and severe stenosis. Acta Otorrinolaringol 64:339–344

    Article  Google Scholar 

  11. Bajaj Y, Cochrane LA, Jephson CG, Wyatt ME, Bailey CM, Albert DM, Hartley BEJ (2012) Laryngotracheal reconstruction and cricotracheal resection in children: recent experience at Great Ormond Street Hospital. Int J Pediatr Otorhinolaryngol 76:507–511

    Article  CAS  Google Scholar 

  12. Gallo A, Pagliuca G, Greco A, Martellucci S, Mascelli A, Fusconi M, De Vincentiis M (2012) Laryngotracheal stenosis treated with multiple surgeries: experience, results and prognostic factors in 70 patients. Acta Otorhinolaryngol Ital 32:182

    CAS  PubMed  PubMed Central  Google Scholar 

  13. Alshammari J, Alkhunaizi AA, Arafat AS (2017) Tertiary center experience with primary endoscopic laryngoplasty in pediatric acquired subglottic stenosis and literature review. Int J Pediatr Adolesc Med 4:33–37

    Article  Google Scholar 

  14. Jethwa AR, Hasan W, Palme CE, Mäkitie AA, Espin-Garcia O, Goldstein DP, Gilbert RW, Keshavjee S, Pierre A, Gullane PJ (2020) Cricotracheal resection for adult subglottic stenosis: Factors predicting treatment failure. Laryngoscope 130:1634–1639

    Article  Google Scholar 

  15. Hartley BEJ, Gustafson LM, Hartnick CJ, Liu JH, Cotton RT (2001) Duration of stenting in single-stage laryngotracheal reconstruction with anterior costal cartilage grafts. Ann Otol Rhinol Laryngol 110:413–416

    Article  CAS  Google Scholar 

  16. Hartley BEJ, Willging JP, Hartnick CJ, Lacy PD, Myer CM III, Liu J, Cotton RT (2001) Surgery for pediatric subglottic stenosis: disease-specific outcomes. Ann Otol Rhinol Laryngol 110:1109–1113

    Article  Google Scholar 

  17. Saunders MW, Thirlwall A, Jacob A, Albert DM (1999) Single-or-two-stage laryngotracheal reconstruction; comparison of outcomes. Int J Pediatr Otorhinolaryngol 50:51–54

    Article  CAS  Google Scholar 

  18. Lahav Y, Shoffel-Havakuk H, Halperin D (2015) Acquired glottic stenosis—the ongoing challenge: a review of etiology, pathogenesis, and surgical management. J Voice 29:646-e1

    Article  Google Scholar 

  19. Smith DF, de Alarcon A, Jefferson ND, Tabangin ME, Rutter MJ, Cotton RT, Hart CK (2018) Short-versus long-term stenting in children with subglottic stenosis undergoing laryngotracheal reconstruction. Otolaryngol Neck Surg 158:375–380

    Article  Google Scholar 

  20. Stern Y, Willging JP, Cotton RT (1998) Use of Montgomery® T-tube in laryngotracheal reconstruction in children: Is it safe? Ann Otol Rhinol Laryngol 107:1006–1009

    Article  CAS  Google Scholar 

  21. Preciado D (2014) A randomized study of suprastomal stents in laryngotracheoplasty surgery for grade III subglottic stenosis in children. Laryngoscope 124:207–213

    Article  Google Scholar 

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Acknowledgements

The authors grateful acknowledge the cooperation of the study setting administration.

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The author(s) received no financial support for the research, authorship, and/or publication of this article.

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TAK, brought idea, main surgeon, revised manuscript, approved submission. AK, revised the data. WAM, data analysis, wrote manuscript. AM, data collection, participated in writing manuscript. TA, data collection.

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Correspondence to Wafa Abdullah Maqbul.

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Authors declared that they have no conflict of interest.

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The study was approved by the Institutional Research Ethics Committee (Reference No 207–19).

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The authors declare that there are no competing interests.

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Al-Khatib, T., Kurdi, A., Maqbul, W.A. et al. Treatment of Childhood High-Grade Subglottic Stenosis (SGS) Through Laryngotracheoplasty (LTP) in a Tertiary Pediatric Center from 2013 to 2020. Indian J Otolaryngol Head Neck Surg 74, 363–368 (2022). https://doi.org/10.1007/s12070-021-02767-7

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  • DOI: https://doi.org/10.1007/s12070-021-02767-7

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