Abstract
Free flap has become crucial for reconstruction in head and neck oncology post resection since the time of its advent. It has shown a high success rate and provides a better quality of life over loco regional flaps. Literature has shown the success of free flaps does get influenced by preexisting medical conditions of the patient. Nephrotic syndrome being a hypercoagulable state doesn’t find much mention in literature and its effect on free flaps has been less studied. Hence, using a free flap in such condition creates a decision making dilemma. Here we present a case report to show the feasibility of such flaps in nephrotic syndrome patients under structured environment successfully.
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References
Llach F (1985) Hypercoagulability, renal vein thrombosis, and other thrombotic complications of nephrotic syndrome. Kidney Int 28:429–439
Singhal R, Brimble KS (2006) Thromoembolic complications in the nephrotic syndrome, pathophysiology and clinical management. Thromb Res 118:397–407
Mahmoodi BK, Kate MKT, Waanders F et al (2008) High absolute risks and predictors of venous and arterial thromboembolic events in patients with nephrotic syndrome. Results from a large retrospective cohort study. Circulation 117:224–230
Al-Thunayyan A, Al-Dekhayel SA, Al-Namla A, Al-Qattan MM (2009) Free flaps in nephrotic syndrome patients. J Plast Reconstr Aesthet Surg 62(4):555–556
Karakawa R, Yoshimatsu H, Narushima M, Iida T (2018) Ratio of blood glucose level change measurement for flap monitoring. Plast Reconstr Surg Glob Open 6(7):e1851
Bick RL, Ucar K (1992) Hypercoagulability and thrombosis. Hematol Oncol Clin N Am 6(6):1421–1431
Farkas JC, Tabet G, Marzelle J, Cormier F, Laurian C, Cormier JM (1993) Arterial thrombosis: a rare complication of the nephrotic syndrome. Cardiovasc Surg 1(3):265–269
Siddiqi FA, Tepler J, Fantini GA (1997) Aquired protein S and antithrombin III deficiency caused by nephrotic syndrome: an unusual cause of graft thrombosis. J Vasc Surg 25:576–580
Al-Qattan MM, Bowen V (1993) The effect of pre-existing health conditions on the results of reconstructive microvascular surgery. Microsurgery 14:152–157
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Sinha, P., Singh, V. & Siddiqui, E. Free Flap Reconstruction in a Tongue Cancer Patient with Nephrotic Syndrome: A Case Report. Indian J Otolaryngol Head Neck Surg 74 (Suppl 3), 5814–5816 (2022). https://doi.org/10.1007/s12070-021-02406-1
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DOI: https://doi.org/10.1007/s12070-021-02406-1