Hyalinizing clear cell carcinoma (HCCC) is a low grade, rare neoplasm originating from the minor salivary glands. It usually follows an indolent course and the main treatment modality is surgery. The prognosis of these tumours are good, hence it needs to be differentiated from other carcinomas with clear cells. Here we report a pathologically proven HCCC of the base of tongue.
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Milchgrub S, Gnepp DR, Vuitch F, Delgado R, Albores-Saavedra J (1994) Hyalinizing clear cell carcinoma of salivary gland. Am J Surg Pathol 18:74–82
Balakrishnan R, Nayak DR, Pillai S et al (2002) Hyalinizing clear cell carcinoma of the base of the tongue. J Laryngol Otol 116:851–853
Daniele L, Nikolarakos D, Keenan J et al (2016) Clear cell carcinoma, not otherwise specified/hyalinising clear carcinoma of the salivary gland: the current nomenclature, clinical/pathological characteristics and management. Crit Rev Oncol Hematol 102:55–64
O’Sullivan-Mejia ED, Massey HD, Faquin WC, Powers CN (2009) Hyalinizing clear cell carcinoma: report of eight cases and a review of literature. Head Neck Pathol 3(3):179–185
Masilamani S, Rao S, Chirakkal P, Kumar AR (2011) Hyalinising clear cell carcinoma of the base of tongue: a distinct and rare entity. Indian J Pathol Microbiol 54(1):167–169
Farooq S, Harding-Jackson N, Stadler M, Freitag F (2016) Hyalinizing clear cell carcinoma of the base of tongue: first report of a case presenting with headaches. Neurology 86(16):P6.094
Suzuki H, Katoh A, Udaka T, Shiomori T, Fujimura T, Fujimura K, Kitamura T (2006) Hyalinizing clear cell carcinoma arising from the base of the tongue. Acta Otolaryngol 126(6):653–656
Pujary K, Rangarajan S, Nayak DR, Balakrishnan R, Ramakrishnan V (2008) Hyalinizing clear cell carcinoma of the base of tongue. Int J Oral Maxillofac Surg 37(1):93–96 Epub 2007 Sep 5
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The authors declare that they have no conflict of interest.
Formal consent is not required for this type of study (clinical report). Informed consent was obtained from the patient for the surgical procedure.
All procedures performed in the study were in accordance with the ethical standards of the institution and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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Pillai, N., Balasundaram, P. & Isaac, N. Hyalinizing Clear Cell Carcinoma: Base of Tongue. Indian J Otolaryngol Head Neck Surg 71, 239–242 (2019). https://doi.org/10.1007/s12070-018-01573-y
- Hyalinizing clear cell carcinoma
- Base of tongue
- Minor salivary gland tumour