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Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Squamous cell carcinoma (SCC) of the tongue is the most common oral cancer. Most cases occur on the lateral border of the tongue and only very rarely on the dorsum. We retrospectively investigated the incidence of SCC of the tongue dorsum in our department between April 2006 and March 2015. Of the 368 patients with tongue cancer, only 3 had SCC of the tongue dorsum (incidence, 0.8 %). All patients with advanced cancer of the tongue dorsum underwent superselective intra-arterial chemoradiotherapy for organ preservation. We discuss the present findings in relation to past case reports and series in the English language literature as well as discuss treatments for SCC of the tongue dorsum.

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References

  1. Frazell EL, Lucas JC Jr (1962) Cancer of the tongue. Report of the management of 1,554 patients. Cancer 15:1085–1099

    Article  CAS  PubMed  Google Scholar 

  2. Flamant R, Hayem M, Lazar P et al (1964) Cancer of the tongue. A study of 904 cases. Cancer 17:377–385

    Article  CAS  PubMed  Google Scholar 

  3. Saxena VS (1970) Cancer of the tongue: local control of the primary. Cancer 26:788–794

    Article  CAS  PubMed  Google Scholar 

  4. Mendelson BC, Woods JE, Beahrs OH (1976) Neck dissection in the treatment of carcinoma of the anterior two-thirds of the tongue. Surg Gynecol Obstet 143:75–80

    CAS  PubMed  Google Scholar 

  5. Kari S, Alho OP, Jokinen K et al (1997) Carcinoma of the oral tongue in northern Finland: trends in overall incidence and patient and tumor characteristics. J Oral Pathol Med 26:480–483

    Article  CAS  PubMed  Google Scholar 

  6. Goldenberg D, Ardekian L, Rachmiel A et al (2000) Carcinoma of the dorsum of the tongue. Head Neck 22:190–194

    Article  CAS  PubMed  Google Scholar 

  7. Katz RW, Brahim JS, Travis WD (1990) Oral squamous cell carcinoma arising in a patient with long-standing lichen planus. A case report. Oral Surg Oral Med Oral Pathol 70:282–285

    Article  CAS  PubMed  Google Scholar 

  8. Coombes D, Cascarini L, Booth PW (2008) Carcinoma of the midline dorsum of the tongue. Br J Oral Maxillofac Surg 46:485–486

    Article  PubMed  Google Scholar 

  9. Camisa C, Hamaty FG, Gay JD (1998) Squamous cell carcinoma of the tongue arising in lichen planus: a case report and review of the literature. Cutis 62:175–178

    CAS  PubMed  Google Scholar 

  10. Pogrel MA, Weldon LL (1983) Carcinoma arising in erosive lichen planus in the midline of the dorsum of the tongue. Oral Surg Oral Med Oral Pathol 55:62–66

    Article  CAS  PubMed  Google Scholar 

  11. Fowler CB, Rees TD, Smith BR (1987) Squamous cell carcinoma on the dorsum of the tongue arising in a long-standing lesion of erosive lichen planus. J Am Dent Assoc 115:707–710

    Article  CAS  PubMed  Google Scholar 

  12. Burkes EJ, Lewis JR (1976) Carcinoma arising in the area of median rhomboid glossitis. Oral Surg Oral Med Oral Pathol 41:649–652

    Article  CAS  PubMed  Google Scholar 

  13. Gorsky M, Raviv M, Taicher S (1993) Squamous cell carcinoma mimicking median rhomboid glossitis region: report of a case. J Oral Maxillofac Surg 51:798–800

    Article  CAS  PubMed  Google Scholar 

  14. Sharp GS, Bullock WK (1958) Carcinoma arising in glossitis rhombica mediana. Cancer 11:148–150

    Article  CAS  PubMed  Google Scholar 

  15. Pastore L, Fiorella ML, Fiorella R et al (2008) Multiple masses on the tongue of a patient with generalized mucocutaneous lesions. Pros Med 5:e212

    Google Scholar 

  16. Ogus HD, Bennett MH (1978) Carcinoma of the dorsum of the tongue: a rarity or misdiagnosis. Br J Oral Surg 16:115–124

    Article  CAS  PubMed  Google Scholar 

  17. Mitsudo K, Shigetomi T, Fujimoto Y et al (2011) Organ preservation with daily concurrent chemoradiotherapy using superselective intra-arterial infusion via a superficial temporal artery for T3 and T4 head and neck cancer. Int J Radiat Oncol Biol Phys 79:1428–1435

    Article  PubMed  Google Scholar 

  18. Dziegielewski PT, Ho ML, Rieger J et al (2013) Total glossectomy with laryngeal preservation and free flap reconstruction: objective functional outcomes and systematic review of the literature. Laryngoscope 123:140–145

    Article  PubMed  Google Scholar 

  19. Rihani J, Lee MR, Lee T et al (2013) Flap selection and functional outcomes in total glossectomy with lalyngeal preservation. Otolaryngol Head Neck Surg 149:547–553

    Article  PubMed  Google Scholar 

  20. McDowell L, Collins M, Kleid S et al (2014) T4 squamous cell carcinoma of the tongue without mandibular involvement: surgery or chemoradiotherapy? Oral Surg Oral Med Oral Pathol Oral Radiol 117:163–169

    Article  PubMed  Google Scholar 

  21. Stenson KM, Kunnavakkam R, Cohen EE et al (2010) Chemoradiation for patients with advanced oral cavity cancer. Laryngoscope 120:93–99

    Article  PubMed  Google Scholar 

  22. Pederson AW, Haraf DJ, Witt ME et al (2010) Chemoradiotherapy for locoregionally advanced squamous cell carcinoma of the base of tongue. Head Neck 32:1519–1527

    Article  PubMed  Google Scholar 

  23. Fuwa N, Kodaira T, Furutani K et al (2008) Arterial chemoradiotherapy for locally advanced tongue cancer: analysis of retrospective study of therapeutic results in 88 patients. Int J Radiat Oncol Biol Phys 72:1090–1100

    Article  CAS  PubMed  Google Scholar 

  24. Tohnai I (2006) Chemotherapy using intra-arterial infusion for oral cancer. Nagoya J Med Sci 68:101–108

    CAS  PubMed  Google Scholar 

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Correspondence to Toshinori Iwai.

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All authors declare no conflicts of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Okubo, M., Iwai, T., Nakashima, H. et al. Squamous Cell Carcinoma of the Tongue Dorsum: Incidence and Treatment Considerations. Indian J Otolaryngol Head Neck Surg 69, 6–10 (2017). https://doi.org/10.1007/s12070-016-0979-z

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  • DOI: https://doi.org/10.1007/s12070-016-0979-z

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