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Ectopic Esthesioneuroblastoma of the Sphenoclivus: A Rare Entity

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Abstract

Esthesioneuroblastoma is a rare malignant neoplasm of oflactory neuroepithelium and usually located at the olfactory cleft at superior nasal cavity. Ectopic localization of esthesioneuroblastoma is even rarer and usually posed with a diagnostic dilemma and delay in the diagnosis and management, We report a rare case of ectopic esthesioneuroblastoma of the sphenoclivus with the presentation of intermittent unilateral epistaxis, intermittent intractable headache without anosmia. Nasal endoscopy findings showed a pulsatile mass at the anterior face of the sphenoid sinus with extension posteriorly towards the clivus region and occupying the floor of the sphenoid sinus. Endonasal transclival endoscopic excision of tumour was performed which involved otorhinolaryngology surgeon and neurosurgeon with intraoperative navigation imaging and frozen section. The histopathological findings was esthesioneuroblastoma. Due to its rarity and unusual presentation, the diagnosis of ectopic esthesioneuroblastoma is difficult and can be misdiagnosed with the other type of malignancy. Therefore, the histopathological result is important in confirming the type of tumour and can lead to the next step of management.

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Acknowledgments

The authors would like acknowledge the Associate Professor Dr. Richard J. Harvey, Macquarie University and University of New South Wales, Sydney, Australia. Ramez Kirollos, Cambridge University Hospital, United Kingdom.

Funding

This study was not funded by any institution, company or organisation.

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Authors and Affiliations

  1. Department of Otorhinolaryngology-Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Jalan Ya’acob Latif, Bandar Tun Razak, Cheras, 56000, Kuala Lumpur, Malaysia

    Farah Dayana Zahedi, Balwant Singh Gendeh & Salina Husain

  2. Neurosurgery Unit, Department of Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia

    Ramesh Kumar

  3. Department of Radiology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia

    Thean Yean Kew

Authors
  1. Farah Dayana Zahedi
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  2. Balwant Singh Gendeh
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  3. Salina Husain
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  4. Ramesh Kumar
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  5. Thean Yean Kew
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Corresponding author

Correspondence to Farah Dayana Zahedi.

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Conflict of interest

Dr. Farah Dayana Zahedi, Professor Dato’ Dr. Balwant Singh Gendeh Associate Professor Dr. Salina Husain and Associate Professor Dr. Ramesh Kumar and Dr. Kew Thean Yean declare that they have no conflict of interest.

Ethical Approval

This case reports only involved a review on a patient’s case. This article does not contain any experimental studies with human participants or animals performed by any of the authors.

Informed Consent

Informed consent was obtained from the individual included in this case report.

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Zahedi, F.D., Gendeh, B.S., Husain, S. et al. Ectopic Esthesioneuroblastoma of the Sphenoclivus: A Rare Entity. Indian J Otolaryngol Head Neck Surg 69, 125–129 (2017). https://doi.org/10.1007/s12070-016-0978-0

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  • DOI: https://doi.org/10.1007/s12070-016-0978-0

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