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Mean Platelet Volume: Is It a Predictive Parameter in The Diagnosis of Sudden Sensorineural Hearing Loss?

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

The mean platelet volume (MPV) is associated with increased platelet reactivity and increased atherothrombosis. High MPV values are a risk factor for thrombotic vascular diseases. Our aim was to investigate whether a relationship exists between sudden sensorineural hearing loss (SSHL) and a high MPV value. The records of 46 patients who were admitted to the ENT (ear nose throat) ward for SSHL and received medical treatment and 46 patients in a control group were retrospectively screened. The correlation among the levels of the MPV, the number of platelets, and SSHL were evaluated in the two groups. The ages, genders, and the platelet count values of the patients showed a normal distribution in both groups. No significant difference was found for the MPV values between the groups. The MPV is not a predictive parameter in the diagnosis of SSHL.

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References

  1. Wilson WR, Byl FM, Laird N (1980) The efficacy of steroids in the treatment of idiopathic sudden hearing loss. A doubleblind clinical study. Acta Otolaryngol 106:772–776

    Article  CAS  Google Scholar 

  2. Cadoni G, Agostino S, Manna R et al (2003) Clinical association of serum antiendothelial cell antibodies in patients with sudden sensorineural hearing loss. Laryngoscope 113:797–801

    Article  PubMed  Google Scholar 

  3. Chau JK, Lin JRJ, Atashband S et al (2010) Systematic review of the etiology of adult sudden sensorineural hearing loss. Laryngoscope 120:1011–1021

    Article  PubMed  Google Scholar 

  4. Teranishi M, Katayama N, Uchida Y et al (2007) Thirty-year trends in sudden deafness from four nationwide epidemiological surveys in Japan. Acta Otolaryngol 127:1259–1265

    Article  PubMed  Google Scholar 

  5. Rauch SD (2008) Clinical practice. Idiopathic sudden sensorineural hearing loss. N Engl J Med 359:833–840

    Article  PubMed  CAS  Google Scholar 

  6. Lin HC, Lee HC, Chao PZ (2006) The effects of weather on the incidence of sudden sensorineural hearing loss: a 5-year population-based study. Audiol Neurootol 11:165–171

    Article  PubMed  Google Scholar 

  7. Cadoni G, Agostino S, Scipione S et al (2005) Sudden sensorineural hearing loss: our experience in diagnosis, treatment, and outcome. J Otolaryngol 34:395–401

    Article  PubMed  Google Scholar 

  8. Merchant SN, Durand ML, Adams JC (2008) Sudden deafness: is it viral? ORL J Otorhinolaryngol Relat Spec 70:52–60

    Article  PubMed  Google Scholar 

  9. Agrup C (2008) Immune-mediated audiovestibular disorders in the paediatric population: a review. Int J Audiol 47:560–565

    Article  PubMed  Google Scholar 

  10. Kuhn M, Heman-Ackah SE, Shaikh JA et al (2011) Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis. Trends Amplif 15:91–105

    Article  PubMed  Google Scholar 

  11. Chau JK, Lin JR, Atashband S et al (2010) Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope 120(5):1011–1021

    PubMed  Google Scholar 

  12. Vasama JP, Linthicum FH Jr (2000) Idiopathic sudden sensorineural hearing loss: temporal bone histopathologic study. Ann Otol Rhinol Laryngol 109:527–532

    PubMed  CAS  Google Scholar 

  13. Coppinger JA, Cagney G, Toomey S et al (2004) Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood 103:2096–2104

    Article  PubMed  CAS  Google Scholar 

  14. Gawaz M, Langer H, May AE (2005) Platelets in inflammation and atherogenesis. J Clin Invest 115:3378–3384

    Article  PubMed  CAS  Google Scholar 

  15. Kamath S, Blann AD, Lip GY (2001) Platelet activation: assessment and quantification. Eur Heart J 22:1561–1571

    Article  PubMed  CAS  Google Scholar 

  16. Endler G, Klimesch A, Sunder-Plassmann H et al (2002) Mean platelet volume is an independent risk factor for myocardial infarction but not for coronary artery disease. Br J Haematol 117:399–404

    Article  PubMed  Google Scholar 

  17. Braekkan SK, Mathiesen EB, Njølstad I et al (2010) Mean platelet volume is a risk factor for venous thromboembolism: the Tromsø study. J Thromb Haemost 8:157–162

    Article  PubMed  CAS  Google Scholar 

  18. Kyrle PA, Hron G, Eichinger S et al (2007) Circulating P-selectin and the risk of recurrent venous thromboembolism. Thromb Haemost 97:880–883

    PubMed  CAS  Google Scholar 

  19. Chu SG, Becker RC, Berger PB et al (2010) Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. J Thromb Haemost 8:148–156

    Article  PubMed  CAS  Google Scholar 

  20. Bath P, Algert C, Chapman N et al (2004) Association of mean platelet volume with risk of stroke among 3134 individuals with history of cerebrovascular disease. Stroke 35:622–626

    Article  PubMed  Google Scholar 

  21. Kiliçli-Camur N, Demirtunç R, Konuralp C et al (2005) Could mean platelet volume be a predictive marker for acute myocardial infarction? Med Sci Monit 11:387–392

    Google Scholar 

  22. Rasmussen H (1949) Sudden deafness. Acta Otolaryngol 37:65–70

    Article  Google Scholar 

  23. Ballesteros F, Alobid I, Tassies D et al (2009) Is there an overlap between sudden neurosensorial hearing loss and cardiovascular risk factors? Audiol Neurotol 14:139–145

    Article  CAS  Google Scholar 

  24. Capaccio P, Ottaviani F, Cuccarini V (2007) Genetic and acquired prothrombotic risk factors and sudden hearing loss. Laryngoscope 117:547–551

    Article  PubMed  Google Scholar 

  25. Chau JK, Lin JR, Atashband S et al (2010) Systematic review of the evidence for the etiology of adult sudden sensorineural hearing loss. Laryngoscope 120:1011–1021

    Article  PubMed  Google Scholar 

  26. Patzak MJ, Demuth K, Kehl R et al (2005) Lindner A. Sudden hearing loss as the leading symptom of an infarction of the left anterior inferior cerebellar artery. HNO 53:797–799

    Article  PubMed  CAS  Google Scholar 

  27. Lee H, Kim HJ, Koo JW et al (2009) Progression of acute cochleovestibulopathy into anterior inferior cerebellar artery infarction. J Neurol Sci 278:119–122

    Article  PubMed  Google Scholar 

  28. Lee H, Ahn BH, Baloh RW (2004) Sudden deafness with vertigo as a sole manifestation of anterior inferior cerebellar artery infarction. J Neurol Sci 15:105–117

    Article  Google Scholar 

  29. Rajesh R, Rafeequ M, Girija AS (2004) Anterior inferior cerebellar artery infarct with unilateral deafness. J Assoc Phys India 52:333–334

    CAS  Google Scholar 

  30. Schuknecht HF (1993) Pathology of the Ear, 2nd edn. Lea and Febiger, Philadelphia, p 672

    Google Scholar 

  31. Perlman HB, Kimura RS, Fernandez C (1959) Experiments on temporary occlusion of the internal auditory artery. Laryngoscope 69:591–613

    Article  PubMed  CAS  Google Scholar 

  32. Merchant SN, Adams JC, Nadol JB (2005) Pathology and pathophysiology of idiopathic sudden sensorineural hearing loss. Otol Neurotol 26:151–160

    Article  PubMed  Google Scholar 

  33. Beal DD, Hemenway WG, Lindsay JR (1967) Inner ear pathology of sudden deafness. Arch Otolaryngol 85:591–598

    Article  PubMed  CAS  Google Scholar 

  34. Vasama JP, Linthicum FH Jr (2000) Idiopathic sudden sensorineural hearing loss: temporal bone histopathologic study. Ann Otol Rhinol Laryngol 109:527–532

    PubMed  CAS  Google Scholar 

  35. Bahmad F Jr (2008) Temporal bone histopathology: idiopathic sudden hearing loss. Braz J Otorhinolaryngol 74:159

    Google Scholar 

  36. Bath PM, Butterworth RJ (1996) Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 7:157–161

    Article  PubMed  CAS  Google Scholar 

  37. Breimo ES, Osterud B (2003) Studies of biological functions in blood cells from individuals with large platelets. Platelets 14:413–419

    Article  PubMed  CAS  Google Scholar 

  38. Pathansali R, Smith NM, Bath PM (2001) Prothrombotic megakaryocyte and platelet changes in hypertension are reversed following treatment: a pilot study. Platelets 12:144–149

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Otorhinolaryngology, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey

    Rifat Karli, Recep Unal, Harun Kucuk, Ahmet Aksoy & Emre Ayhan

  2. Department of Clinical Biochemistry, School of Medicine, Ondokuz Mayıs University, Samsun, Turkey

    Hasan Alacam

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  1. Rifat Karli
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  2. Hasan Alacam
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  3. Recep Unal
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  4. Harun Kucuk
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  5. Ahmet Aksoy
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  6. Emre Ayhan
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Correspondence to Rifat Karli.

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Karli, R., Alacam, H., Unal, R. et al. Mean Platelet Volume: Is It a Predictive Parameter in The Diagnosis of Sudden Sensorineural Hearing Loss?. Indian J Otolaryngol Head Neck Surg 65, 350–353 (2013). https://doi.org/10.1007/s12070-013-0648-4

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  • DOI: https://doi.org/10.1007/s12070-013-0648-4

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