Abstract
Kimura’s disease is chronic inflammatory disorder of unknown etiology that most commonly present as painless, unilateral cervical lymphadenopathy, males are more commonly effected than females with 3.5:1–9:1 ratio. Kimura’s disease commonly seen in young adults median age being 28–32 years. Here we are presenting a case of Kimura’s disease in a 6 year old male child, with a bilateral presentation. The goals of pharmacotherapy for Kimura’s disease are to reduce morbidity and to prevent complications. The prognosis for Kimura’s disease is good with no potential for malignant transformation.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Kimm HT, Szeto C (1937) Eosinophilic hyperplastic lymphogranuloma, comparison with Mikulicz’s disease. Proc Chin Med Soc 329
Kimura’s T, Yoshimura S, Ishikawa E (1948) On the unusual granulation combined with hyperplastic changes of lymphatic tissues. Trans Soc Pathol Jpn 37:179–180
Thomas J, Jayachandran NV, Chandrasekhara PK, Rajasekhar L, Narsimulu G (2008) Kimura’s disease–an unusual cause of lymphadenopathy in children. Clin Rheumatol 27(5):675–677
Mrówka-Kata K, Kata D, Kyrcz-Krzemien S, Helbig G (2009) Kikuchi-Fujimoto and Kimura’s diseases: the selected, rare causes of neck lymphadenopathy. Eur Arch Otorhinolaryngol Oct 16 2009
Rajpoot DK, Pahl M, Clark J (2000) Nephrotic syndrome associated with Kimura’s disease. Pediatr Nephrol 14(6):486–488
Wang DY, Mao JH, Zhang Y et al (2009) Kimura’s disease: a case report and review of the Chinese literature. Nephron Clin Pract 111(1):c55–c61
Sun QF, Xu DZ, Pan SH et al (2008) Kimura’s disease: review of the literature. Intern Med J 38(8):668–672
Kung IT, Gibson JB, Bannatyne PM (1984) Kimura’s disease: a clinico-pathological study of 21 cases and its distinction from angiolymphoid hyperplasia with eosinophilia. Pathology 16(1):39–44
Chen H, Thompson LD, Aguilera NS, Abbondanzo SL (2004) Kimura’s disease: a clinicopathologic study of 21 cases. Am J Surg Pathol 28(4):505–513
Masayuki S, Ayako K, Shinichi N (2005) Hematoserological analysis of Kimura’s disease for optimal treatment. Otolaryngol Head Neck Surg 132:159–160
Ohta N, Okazaki S, Fukase S, Akatsuka N, Aoyagi M, Yamakawa M (2007) Serum concentrations of eosinophil cationic protein and eosinophils of patients with Kimura’s disease. Allergol Int 56(1):45–49
Takeishi M, Makino Y, Nishioka H, Miyawaki T, Kurihara K (2007) Kimura’s disease: diagnostic imaging findings and surgical treatment. J Craniofac Surg 18(5):1062–1067
Hareyama M, Oouchi A, Nagakura H et al (1998) Radiotherapy for Kimura’s disease: the optimum dosage. Int J Radiat Oncol Biol Phys 40(3):647–651
Kaneko K, Aoki M, Hattori S, Sato M, Kawana S (1999) Successful treatment of Kimura’s disease with cyclosporine. J Am Acad Dermatol 41(5 Pt 2):893–894
Hongcharu W, Baldassano M, Taylor CR (2000) Kimura’s disease with oral ulcers: response to pentoxifylline. J Am Acad Dermatol 43(5 Pt 2):905–907
Boulanger E, Gachot B, Verkarre V, Valensi F, Brousse N, Hermine O (2002) all-trans-Retinoic acid in the treatment of Kimura’s disease. Am J Hematol 71(1):66
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Shankar, T., MyReddy, N. & Varalaxmi, K.P. Kimura’s Disease: A Case Report in a Child. Indian J Otolaryngol Head Neck Surg 66 (Suppl 1), 237–241 (2014). https://doi.org/10.1007/s12070-011-0446-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12070-011-0446-9