Abstract
Neck is the most common site of peripheral lymph node enlargement and is very frequently encountered in oto-laryngological practice. This study was done to delineate distribution of clinico-demographic parameters in patients presenting with cervical lymphadenopathy in the otolaryngology out-patient department of a state hospital in India in a 1 year period and to correlate them with fine needle aspiration cytological diagnosis. Record-based cross sectional study in the department of Otolaryngology and department of Pathology, Calcutta National Medical College and Hospital, Kolkata. Case reports and cytological reports of 423 patients who underwent Fine Needle Aspiration Cytology (FNAC) of cervical lymph nodes between January 2009 and December 2009 were reviewed in relation to their demographic and clinical profiles. The cases were divided into three groups according to age and different parameters were described according to these groups. In the cyto-pathological diagnosis, tubercular lymph-adenitis was most prevalent diagnosis (45.4%). Among the metastatic secondaries, squamous cell carcinoma was most common (8.5%). Non-specific/reactive lymphadenitis was significantly more common in <14 years, TB lymph node in 15–59 years and malignancy among the ≥60 years age group. Jugulo-omohyoid (level III) and Supraclavicular (level VB) groups of Lymph nodes were found significantly more involved by malignancy whereas Jugulo-diagastric (level II), Post-auricular, Submandibular groups (level IB) were more commonly involved in TB. Malignancy patients presented late in respect to the tuberculosis patients. Knowledge about clinico-demographic perspectives of cervical lymphadenopathy in respect to their cytopathological diagnosis will help care giver practioners to detect/refer the respective cases early for investigations and treatment.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Papadepouli E, Michaillidi E, Papadopoulou E, Paspalki P, Vlahakis I, Kalmanti M (2009) Cervical lymphadenopathy in childhood epidemiology and management. Pediatr Hematol Oncol 26(6):454–460
Bazemore AW, Smucker DR (2002) Lymphadenopathy and malignancy. Am Fam Physician 66:2103–2110
Layfield LJ (1996) Fine-needle aspiration of the head and neck. Pathology 4(2):409–438
Reddy MP, Moorchung N, Chaudhary A (2002) Clinico-pathological profile of pediatric lymphadenopathy. Ind J Pediatrics 69(12):1047–1051
Narang RK, Pradhan S, Singh RP, Chaturvedi S (1990) Place of fine needle aspiration cytology in the diagnosis of lymphadenopathy. Ind J Tub 37:29–31
Ahmad SS, Akhtar S, Akhtar K, Naseem S, Mansoor T (2005) Study of fine needle aspiration cytology in lymphadenopathy: with special reference to acid fast staining in cases of tuberculosis. JK Science 7(1):1–4
Khan RA, Wahab S, Chana RS, Naseem S, Siddique S (2008) Children with significant cervical lymphadenopathy: clinicopathological analysis and role of fine-needle aspiration in Indian setup. J Pediatr 84(5):449–454
Shakya G, Malla S, Shakya KN, Shrestha R (2009) A Study of FNAC of cervical lymph nodes. J Nepal Health Res Counc 7(14):1–5
Bhatt JV, Shah JM, Shah F (2002) Clinico-pathological profile of cervical lymphadenopathy: a prospective study. J Appl Basic Med Sci 2(2):35–39 [http://www.nhlmmcgym.com/clinico-pathological-profile-cervical.htm. Retrieved June 5 2010]
Shaikh SM, Balochi I, Bhatti Y, Shah AA, Shaikh GS, Deenari RA (2010) An audit of 200 cases of cervical lymphadenopathy. Med Channel 16(1):85–87
Naeimi N, Sharifa A, Erfanian Y, Velayati A, Izadian S (2009) Differential diagnosis of cervical malignant lymphadenopathy among Iranian patients. Saudi Med J 30(3):377–381
Mansoor I, Sayed AA (2002) Cervical lymph node biopsy: clinical and histological significance. Saudi Med J 23(10):1291–1292
Alam K, Haider W, Maheshwari V (2010) Fine needle aspiration cytology (FNAC), a handy tool for metastatic lymphadenopathy. Internet J Pathol 10(2) [http://www.ispub.com/journal/the_internet_journal_of_pathology/volume_10_number_2_13/article/fine-needle-aspiration-cytology-fnac-a-handy-tool-for-metastatic-lymphadenopathy.html. Retrieved June 5 2010]
Khajuria R, Goswami KC, Singh K, Dubbey VK (2006) Pattern of lymphadenopathy on fine needle aspiration cytology in Jammu. JK Science 8(3):157–159
Biswas PK, Begum Sm KN (2007) Tubercular lymphadenopahy: clinico-pathological study of thirty cases. TAJ 20(1):36–38
Chhabra S (2006) A retrospective histopathological evaluation of non-neoplastic superficial lymphadenopathy. Internet J Intern Med 6(1). Retrieved May 23 2010
Samar G, Jafari Sh, Mwazamie N (1998) Tuberculosis of cervical lymphadenitis: a clinical, pathological and bacteriological study. Acta Medical trainica 36(2):138–140
Dandapath MC, Misra BM, Kar PK (1990) Peripheral lymph node tuberculosis: a review of 80 cases. Br J Surg 77:911–912
Dass A (2001) Cervical tubercular lymphadenopathy; changing clinical pattern and concepts in management. Postgrad Med J 77:185–187
Conflict of interest
The Authors declare presence of NO conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Biswas, G., Das, A., Haldar, D. et al. Clinico-Pathological Correlates of Cervical Lymphadenopathy: A Hospital Based Study. Indian J Otolaryngol Head Neck Surg 65 (Suppl 1), 42–47 (2013). https://doi.org/10.1007/s12070-011-0443-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12070-011-0443-z