Abstract
The objective of the study is to document the clinical, histopathological and immunological findings of epithelial myoepithelial carcinoma (EMEC) which is an uncommon neoplasm. The tumour represents less than 0.5–1% of all salivary gland neoplasms. As per literature, it involves the parotid gland most frequently and rarely, the minor salivary glands. We are reporting a series of four cases of EMEC over a period of one and half years, three from minor salivary glands at different sites and one from the deep lobe of parotid. Interestingly, the pre operative FNAC of all the cases revealed benign pathology. Recurrence occurred in three of them after tumour excision. One patient was subjected to post operative radiotherapy and one patient to chemotherapy. Histopathology and immunohistochemistry is very important in this tumour. There is no definitive guideline of treatment in post operative recurrence cases.
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References
Luna AM (2001) Salivary glands. Head and neck surgical pathology. Lippincott Williams and Wilkins, Batski, Philadelphia, pp 292–349
Brocheriou C, Auriol M, de Roquancourt A et al (1991) Epilthelial-myoepithelial carcinoma of salivary glands. Study of 15 cases and review of the literature. Ann Pathol 11(5–6):316–325
Cho KJ, El-Naggar AK, Ordonez NG et al (1995) Epithelial-myoepithelial carcinoma of salivary glands. A clinicopathologic, DNA flow cytometry, and immunohistochemical study of Ki-67 and HER-2/neu oncogene. Am J Clin Pathol 103(4):432–437
Wai-kuen Ng, Carolyn Choy, Philip Ip et al (1999) Fine needle aspiration cytology of epithelial-myoepithelial carcinoma of salivary glands: a report of three cases. Acta Cytol 43:675–680
Simpson RHW, Clarke TJ, Sarsfield PTL, Gluckman PGC (1991) Epithelial-myoepithelial carcinoma salivary glands. J Clin Pathol 44:419–423
Lee HM, Kim AR, Lee SH (2000) Epithelial-myoepithelial carcinoma of the nasal cavity. Arch Otorhinolaryngol 257(7):376–378
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Arora, S.K., Sharma, N. & Bhardwaj, M. Epithelial Myoepithelial Carcinoma of Head and Neck Region. Indian J Otolaryngol Head Neck Surg 65 (Suppl 1), 163–166 (2013). https://doi.org/10.1007/s12070-011-0414-4
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DOI: https://doi.org/10.1007/s12070-011-0414-4