Abstract
Medical records were reviewed to identify subjects who ranged in age from 1 to 18 years and who had undergone tonsillectomy with or without adenoidectomy. Data obtained included patient demographic information, relevant medical history, history of hemorrhage, family history of hemorrhagic disorders, and drug history. Laboratory data obtained included a baseline coagulation screening to determine prothrombin time, activated partial thromboplastin time, and platelet count. Values were classified as within normal limits or as abnormally prolonged according to the local laboratory reference values. The incidence of postoperative hemorrhage in healthy subjects was evaluated, and the correlation between having a medical history of hemorrhage and an abnormal coagulation screen was assessed. We found that the medical history of the patients studied had positive predictive value of 42.8%, and a negative predictive value of 99.1%. The preoperative coagulation screening had a positive predictive value of 50%, and a negative predictive value of 93.6%.
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Derkay CS (1993) Pediatric otolaryngology procedures in the United States: 1977–1987. Int J Pediatr Otorhinolaryngol 25(1–3):1–12
Carithers JS, Gebhart DE, Williams JA (1987) Postoperative risks of pediatric tonsilloadenoidectomy. Laryngoscope 97(4):422–429
Goycoolea MV, Cubillos PM, Martinez GC (1982) Tonsillectomy with a suction coagulator. Laryngoscope 92(7 Pt 1):818–819
Mann DG, St George C, Scheiner E, Granoff D, Imber P, Mlynarczyk FA (1984) Tonsillectomy—some like it hot. Laryngoscope 94(5 Pt 1):677–679
Roy A, De la Rosa C, Vecchio YA (1976) Bleeding following tonsillectomy. A study of electrocoagulation and ligation techniques. Arch Otolaryngol 102(1):9–10
Manning SC, Beste D, McBride T, Goldberg A (1987) An assessment of preoperative coagulation screening for tonsillectomy and adenoidectomy. Int J Pediatr Otorhinolaryngol 13(3):237–244
Kang J, Brodsky L, Danziger I, Volk M, Stanievich J (1994) Coagulation profile as a predictor for post-tonsillectomy and adenoidectomy (T+A) hemorrhage. Int J Pediatr Otorhinolaryngol 28(2–3):157–165
Howells RC II, Wax MK, Ramadan HH (1997) Value of preoperative prothrombin time/partial thromboplastin time as a predictor of postoperative hemorrhage in pediatric patients undergoing tonsillectomy. Otolaryngol Head Neck Surg 117(6):628–632
Burk CD, Miller L, Handler SD, Cohen AR (1992) Preoperative history and coagulation screening in children undergoing tonsillectomy. Pediatrics 89(4 Pt 2):691–695
Gabriel P, Mazoit X, Ecoffey C (2000) Relationship between clinical history, coagulation tests, and perioperative bleeding during tonsillectomies in pediatrics. J Clin Anesth 12(4):288–291
Asaf T, Reuveni H, Yermiahu T et al (2001) The need for routine pre-operative coagulation screening tests (prothrombin time PT/partial thromboplastin time PTT) for healthy children undergoing elective tonsillectomy and/or adenoidectomy. Int J Pediatr Otorhinolaryngol 61(3):217–222
Carmody D, Vamadevan T, Cooper SM (1982) Post tonsillectomy haemorrhage. J Laryngol Otol 96(7):635–638
Rasmussen N (1987) Complications of tonsillectomy and adenoidectomy. Otolaryngol Clin North Am 20(2):383–390
Tami TA, Parker GS, Taylor RE (1987) Post-tonsillectomy bleeding: an evaluation of risk factors. Laryngoscope 97(11):1307–1311
Cochrane AL, Chapman PJ, Oldham PD (1951) Observers’ errors in taking medical histories. Lancet 1(6662):1007–1009
Goddard KE, Broder G, Wenar C (1961) Reliability of pediatric histories. A preliminary study. Pediatrics 28:1011–1018
Gumprecht TF, Cichon JV (1981) Otolaryngology and von Willebrand’s disease. Arch Otolaryngol 107(8):491–493
Bick RL (ed) (1980) A systematic approach to the diagnosis of hemorrhage disorders. CRC Press, Boca Raton
Fuller AM (1981) Evaluation and management of coagulation disorders in elective surgical patients. Laryngoscope 91(9 Pt 1):1484–1500
Rapaport SI (1983) Preoperative hemostatic evaluation: which tests, if any? Blood 61(2):229–231
Bolger WE, Parsons DS, Potempa L (1990) Preoperative hemostatic assessment of the adenotonsillectomy patient. Otolaryngol Head Neck Surg 103(3):396–405
Handler SD, Miller L, Richmond KH, Baranak CC (1986) Post-tonsillectomy hemorrhage: incidence, prevention and management. Laryngoscope 96(11):1243–1247
Eisenberg JM, Goldfarb S (1976) Clinical usefulness of measuring prothrombin time as a routine admission test. Clin Chem 22(10):1644–1647
Hoffman R (2000) Hematology: basic principles and practice, 3rd edn. Churchill Livingston, Philadelphia, pp 1841–1850
Eisenberg JM, Clarke JR, Sussman SA (1982) Prothrombin and partial thromboplastin times as preoperative screening tests. Arch Surg 117(1):48–51
Holmberg L, Nilsson IM (1985) Von Willebrand disease. Clin Haematol 14(2):461–488
Corrigan JJ Jr (1990) Coagulation disorders. In: Smith CH, Miller DR, Baehner RL (eds) Blood diseases of infancy and childhood, 6th edn. CV Mosby, St. Louis, pp 847–895
Ratnoff OD (1979) Hemorrhagic disorders. In: Beeson PB, McDermott W, Wyngaarden JB (eds) Textbook of medicine. WB Saunders Co, Philadelphia, pp 1881–1897
Suchman AL, Mushlin AI (1986) How well does the activated partial thromboplastin time predict postoperative hemorrhage? JAMA 256(6):750–753
Coyas A, Mandalaki T, Tsevrenis H (1967) The importance of preoperative investigations of bleeding tendency in E.N.T. operations. Int Surg 48(1):77–82
Thomas GK, Arbon RA (1970) Preoperative screening for potential T&A bleeding. Arch Otolaryngol 91(5):453–456
Lekas MD, DiBenedetto J Jr, Smith PS, Kantesaria KP (1982) Surgery on patients with hemostatic disorders. Laryngoscope 92(8 Pt 1):873–877
Close HL, Kryzer TC, Nowlin JH, Alving BM (1994) Hemostatic assessment of patients before tonsillectomy: a prospective study. Otolaryngol Head Neck Surg 111(6):733–738
Barber A, Green D, Galluzzo T, Ts’ao CH (1985) The bleeding time as a preoperative screening test. Am J Med 78(5):761–764
Wei JL, Beatty CW, Gustafson RO (2000) Evaluation of posttonsillectomy hemorrhage and risk factors. Otolaryngol Head Neck Surg 123(3):229–235
Houry S, Georgeac C, Hay JM, Fingerhut A, Boudet MJ (1995) A prospective multicenter evaluation of preoperative hemostatic screening tests. The French associations for surgical research. Am J Surg 170(1):19–23
Zwack GC, Derkay CS (1997) The utility of preoperative hemostatic assessment in adenotonsillectomy. Int J Pediatr Otorhinolaryngol 39(1):67–76
Krishna P, Lee D (2001) Post-tonsillectomy bleeding: a meta-analysis. Laryngoscope 111(8):1358–1361
Bachmann F (1980) Diagnostic approach to mild bleeding disorders. Semin Hematol 17(4):292–305
American Academy of Otolaryngology–Head and Neck Surgery, Clinical Indicators Compendium, American Academy of Otolaryngology–Head and Neck Surgery Inc., Alexandria, VA, 1999
Borzotta AP, Keeling MM (1984) Value of the preoperative history as an indicator of hemostatic disorders. Ann Surg 200(5):648–652
Toker A, Shvarts S, Perry ZH, Doron Y, Reuveni H (2004) Clinical guidelines, defensive medicine, and the physician between the two. Am J Otolaryngol 25(4):245–250
Chee YL, Crawford JC, Watson HG, Greaves M (2008) Guidelines on the assessment of bleeding risk prior to surgery or invasive procedures. British Committee for Standards in Haematology. Br J Haematol 140(5):496–504
Nigam A, Ahmed K, Drake-Lee AB (1990) The value of preoperative estimation of haemoglobin in children undergoing tonsillectomy. Clin Otolaryngol Allied Sci 15(6):549–551
Roy WL, Lerman J, McIntyre BG (1991) Is preoperative haemoglobin testing justified in children undergoing minor elective surgery? Can J Anaesth 38(6):700–703
Baron MJ, Gunter J, White P (1992) Is the pediatric preoperative hematocrit determination necessary? South Med J 85(12):1187–1189
Patel RI, DeWitt L, Hannallah RS (1997) Preoperative laboratory testing in children undergoing elective surgery: analysis of current practice. J Clin Anesth 9(7):569–575
Tosetto A, Rodeghiero F, Castaman G et al (2006) A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM-1 VWD). J Thromb Haemost 4(4):766–773
Acknowledgments
We would like to express our gratitude to Dr. Soheir Adam for her invaluable guidance, and special thanks to Dr. Ali Algregry for his co-operation in data collection.
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Zaher, G., Al-Noury, K. The Value of Routine Preoperative Testing in the Prediction of Operative Hemorrhage in Adenotonsillectomy. Indian J Otolaryngol Head Neck Surg 66 (Suppl 1), 30–36 (2014). https://doi.org/10.1007/s12070-011-0285-8
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DOI: https://doi.org/10.1007/s12070-011-0285-8