Skip to main content

Advertisement

Log in

Kawasaki Disease: A Case Report Every Otolaryngologist Should Know

  • Clinical Report
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Kawasaki disease is the acute febrile vasculitis of childhood, predominantly affecting medium sized arteries with predilection for coronary arteries. The diagnosis is mainly clinical, though investigations are helpful in early detection of complications. We report a case of Kawasaki disease in a 5 year old child who presented to our hospital with conjunctival congestion, lymphadenopathy and fever. When on treatment with antibiotics did not help resolve symptoms, particularly conjunctival congestion Kawasaki disease was suspected. She was treated with a single dose of intravenous immunoglobulin G, over a period of 12 h. She subsequently developed a systolic murmur with grade I mitral regurgitation not a known complication of Kawasaki disease. She responded to the treatment remarkably and promptly thus evading any fatal complication.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

References

  1. Laupland KB, Dele Davis H (1999) Epidemiology, etiology, and management of Kawasaki disease: state of art. Pediatr Cardiol 20(3):177–183

    Article  PubMed  CAS  Google Scholar 

  2. Treadwell TA, Maddox RA, Homan RC et al (2002) Investigation of Kawasaki syndrome risk factors in Colorado. Pediatr Infect Dis J 21(10):976–978

    Article  PubMed  Google Scholar 

  3. Nomura Y, Masuda K, Yoshinaga M et al (2004) Possible relationship between streptococcal pyrogenic exotoxin A and Kawasaki syndrome in patients older than six months of age. Pediatr Infec Dis J 23(8):789–791

    Article  Google Scholar 

  4. Shingadia D, Bose A, Booy R (2002) Could a herpes virus be the cause of Kawasaki disease? (Review). Lancet infect Dis 2(5):310–313

    Article  PubMed  CAS  Google Scholar 

  5. Guzman-Cotrill JA, Shulman ST (2004) Recent developments and controversies in Kawasaki disease. Minerva Pediatr 56(1):51–61

    Google Scholar 

  6. Taubert KA, Rowley AH, Shulman ST (1995) In: Kato Hed KD (ed) A 10 year (1984–1993) US hospital survey of Kawasaki disease, 1st edn. Elsevier Science, Amsterdam, pp 34–38

  7. Pannaraj PS, Turner CL, Bastian JF et al (2004) Failure to diagnose Kawasaki disease at the extremes of the paediatric age range. Pediatr Infect Dis J 23(8):789–791

    Article  PubMed  Google Scholar 

  8. Brown TJ, Crawford SE, Cornwall M et al (2001) CD8 T cells and macrophage infiltrate coronary artery aneurysms in acute Kawasaki disease. J Infect Dis 184:940–943

    Article  PubMed  CAS  Google Scholar 

  9. Burns JC, Glode MP (2004) Kawasaki syndrome (review). Lancet 364(9433):533–544

    Article  PubMed  Google Scholar 

  10. Chantepie A, Mauran P, Lusson JR et al (2001) Cardiovascular complications of Kawasaki syndrome: results of a French multicentre study. Arch Pediatr 8(7):713–719

    Article  PubMed  CAS  Google Scholar 

  11. Dajani AS, Taubert KA, Takghashi M et al (1994) Guidelines for long-term management of patients with Kawasaki disease. Circulation 89:916–922

    PubMed  CAS  Google Scholar 

  12. American Heart Association (2001) Council on CVD in young, committee on rheumatic fever, endocarditis and Kawasaki disease: diagnostic guidelines for Kawasaki disease. Circulation 103:335–336

    Google Scholar 

  13. Burns JC, Kushner HI, Bastian JF, Shike H, Shimizu C, Matsubara T, Turner CL (2000) Kawasaki disease–a brief history. Paediatrics 106(2):e27

    Article  CAS  Google Scholar 

  14. Chang RK (2002) Epidemiologic characteristics of children hospitalized for Kawasaki disease in California. Paediatr Infect Dis J 21(12):1150–1155

    Article  Google Scholar 

  15. Gardener-Medwin JM, Dolezalova P, Cummins C, Southwood T (2002) Incidence of Henoch-Schonlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet 360(9341):1197–1202

    Article  Google Scholar 

  16. Brogan PA, Bose A, Burger D, Shingadio D, Tulloh R, Michie C et al (2002) Kawasaki disease: an evidence based approach to diagnosis, treatment and proposal for future research. Arch Dis Child 86(4):286–290

    Article  PubMed  CAS  Google Scholar 

  17. Stiehm ER (1979) Standard and special human immune serum globulins as therapeutic agents. Pediatrics 63:301–319

    PubMed  CAS  Google Scholar 

  18. Furusho K, Sato K, Soeda T et al (1983) High dose intravenous gammaglobulin for Kawasaki disease [letter]. Lancet 2:1359

    Article  PubMed  CAS  Google Scholar 

  19. Nagashima M, Matsushima M, Matsucka H, Ogawa A, Okumura N (1987) High dose gammaglobulin therapy for Kawasaki disease. J Pediatr 110:710–712

    Article  PubMed  CAS  Google Scholar 

  20. Engle MA, Fatica NS, Bussel JB, O’Laughlin JE, Snyder MS, Lesser ML (1989) Clinical trial of single-dose intravenous gammaglobulin in acute Kawasaki disease. AJDC 143:1300–1304

    PubMed  CAS  Google Scholar 

  21. Isawa M, Sugiyama K, Kawase A et al (1986) Prevention of coronary artery involvement in Kawasaki disease by early intravenous high dose gammaglobulin. In: Doyle EF, Engle MA, Gersony WM, Rashkind EJ, Talner NS (eds) Pediatric cardiology. Springer-Verlag, New York, pp 1083–1085

    Google Scholar 

  22. Khubchandani R, D’Souza S (2004) Kawasaki disease in India. Pediatr Rheumatol 2(2):162–171

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Saurav Sarkar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sarkar, S., Dawn, S., Roychoudhury, A. et al. Kawasaki Disease: A Case Report Every Otolaryngologist Should Know. Indian J Otolaryngol Head Neck Surg 63 (Suppl 1), 118–121 (2011). https://doi.org/10.1007/s12070-011-0277-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-011-0277-8

Keywords

Navigation