Abstract
The purpose of presenting these case reports is to highlight the occurrence of heterotopic glial tissue of the tongue and nose in children. So far, literature review has revealed few case reports of such lesions in neonates, but our patients presented with this unique lesion at the age of two and a half years and 3 years. This is a rare congenital anomaly in the tongue, which can mimic a lingual thyroid, teratoma, dermoid cyst etc. Surgical excision is mandatory when the lesion causes obstructive symptoms. The authors discuss the problems in diagnosis, pathology and management and review the literature.
References
Schmidt MB (1900) Ueber seltene spaltbildungen im Bereiche des mittleren Stirn fortsatzes. Arch (Pathol Anat) 162:365
Bratton AB, Robinson SHG (1946) Gliomata of the nose and oral cavity. A report of two cases. J Pathol Bacteriol 58:643
Potter EL (1953) Pathology of the foetus and the new born. Yearbook publishers, Chicago
Mosadomi A (1975) Neurilemmoma of the tongue. J Oral Med 30:44
Ofodile FA, Aghadiuno PU, Oyemade O (1982) Adebonojo T: heterotopic brain in the tongue. Plastic and Reconstr Surg 69:120–124
Orkin M, Fischer I (1966) Heterotopic brain tissue (heterotopic neural rest). Arch Dermatol 94:699–707
Ruff T, Diaz JA (1986) Heterotopic brain in the nasopharynx. Arch Otolaryngol Head Neck Surg 94:254–256
Shapiro MJ (1968) Mix BS: heterotopic brain tissue of the palate. Arch Otolaryngol Head Neck Surg 87:522–526
Genut AA, Miranda FG, Garcia JH (1976) Organized cerebral heterotopia in the ethmoid sinus. J Neurol Sci 28:339–344
Okeda R (1978) Heterotopic brain tissue in the submandibular region and lung—report of two cases and comments about pathogenesis. Acta Neuropathol 43:217–220
Feldman BA, Schwartz RH, Chandra R et al (1982) Heterotopic brain simulating a neonatal tonsil. Clin Pediatr 21:428–430
Smith KR, Schwartz HG, Luse SA et al (1963) Nasal gliomas—A report of five cases with electron microscopy of one. J Neurosurg 20:968–982
Fuller C, Gibbs A (1989) Heterotopic brain tissue in the lung causing acute respiratory distress in an infant. Thorax 44:1045–1046
Knox R, Pratt M, Garvin AJ, White B (1989) Heterotopic lingual brain in the newborn. Arch Otolaryngol Head Neck Surg 115:630–632
Bratton AB, Robinson SHG (1948) Gliomata of the nose and oral cavity: a report of two cases. J Pathol 58:643–648
Batsakis JG (1979) Other neuroectodermal tumors and related lesions of the head and neck in tumors of the head and neck, 2nd edn. Williams & Wilkins, Baltimore, pp 334–337
Patterson K, Kapur S, Chandra RS (1986) Nasal gliomas and related brain heterotopias: a pathologist’s perspective. Pediatr Pathol 5:353–361
Cohen AH, Abt AB (1970) An unusual case of neonatal respiratory obstruction—heterotopic pharyngeal brain tissue. J Pediatr 76:119–122
Kallman JE, Loevner LA, Yousem DM et al (1997) Heterotopic brain in the Pterygopalatine fossa. Am J Neuroradiol 18:176–179
Behar PM, Muller S, Gerber ME, Todd NW (2001) Heterotopic neuroglial tissue causing airway obstruction in the new born. Arch Otolaryngol Head Neck Surg 127:997–1002
Takamizawa S, Inoue T, Ono Y, Satoh S, Nishijima E, Muraji T et al (2006) A case report of glial choristoma of the tongue. J Pediatr Surg 41:E13–E15
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Ramadass, T., Narayanan, N., Rao, P. et al. Glial Heterotopia in ENT—Two Case Reports and Review of Literature. Indian J Otolaryngol Head Neck Surg 63, 407–410 (2011). https://doi.org/10.1007/s12070-011-0267-x
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DOI: https://doi.org/10.1007/s12070-011-0267-x