Abstract
Invasive aspergillosis usually affects immune-compromised patients and is common in diabetics. Proptosis, visual loss and ophthalmoplegia due to intra-orbital extension are common presentations. Three out of five patients in our series were immune-compromised. All the patients had visual loss and three patients presented with unilateral blindness. Three patients were treated by surgical debridement followed by Amphotericin B therapy. Two patients who had intra-cranial extension of the disease died during the treatment. Only one patient had improvement in vision following the treatment. High index of suspicion in immune-compromised patients, early diagnosis and prompt aggressive treatment is required to achieve clinical cure.
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Arora, V., Nagarkar, N.M., Dass, A. et al. Invasive Rhino-Orbital Aspergillosis. Indian J Otolaryngol Head Neck Surg 63, 325–329 (2011). https://doi.org/10.1007/s12070-011-0240-8
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DOI: https://doi.org/10.1007/s12070-011-0240-8