Skip to main content

Advertisement

Log in

Kikuchi-Fujimoto Disease as a Differential Diagnosis for Cervical Lymphadenopathy in India: A Case Report and Review of Literature

  • Clinical Report
  • Published:
Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Cervical Lymphadenopathy has a large list of differential diagnosis. In India, Tuberculosis and Malignant Neoplasms are the most common specific causes for cervical lymph node enlargement. Kikuchi–Fujimoto Disease (KFD), is an uncommon but increasingly reported cause, especially in Asia. Awareness of this condition amongst physicians leads to an accurate diagnosis without the need for expensive and often potentially harmful investigations. The disease is self limiting and responds well to symptomatic treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Deschler DG, Day T (2008) TNM staging of head and neck cancer and neck dissection classification, 3rd edn. American academy of Head and Neck Surgery, Alexandria

    Google Scholar 

  2. Kikuchi M (1972) Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytosis. Nippon Gakkai Zasshi 35:379–380

    Google Scholar 

  3. Fujimoto Y, Kozima Y, Yamaguchi K (1972) Cervical subacute necrotizing lymphadenitis: a new clinicopathological entity. Naika 20:920–927

    Google Scholar 

  4. Bosch X, Guilabert A, Miquel R, Campo E (2004) Enigmatic Kikuchi-Fujimoto disease. A comprehensive review. Am J Clin Pathol 122:141–152

    Article  PubMed  Google Scholar 

  5. Chiu CF, Chow KC, Lin TY et al (2000) Virus infections in patients with histiocytic necrotizing lymphadenitis in Taiwan: detection of Epstein Barr virus, type I human T-cell lymphotropic virus, and parvovirus B19. Am J Clin Pathol 113:774–781

    Article  PubMed  CAS  Google Scholar 

  6. Yen A, Fearneyhough P, Raimer SS et al (1997) EBV-associated Kikuchi’s histiocytic necrotizing lymphadenitis with cutaneous manifestations. J Am Acad Dermatol 36:342–346

    Article  PubMed  CAS  Google Scholar 

  7. Na DG, Chung TS, Byun HS, Kim HD, Ko YH, Yoon JH (1997) Kikuchi disease: CT and MR findings. Am J Neuroradiol 18:1729–1732

    PubMed  CAS  Google Scholar 

  8. Tong TR, Chan OW, Lee KC (2001) Diagnosing Kikuchi disease on fine needle aspiration biopsy: a retrospective study of 44 cases diagnosed by cytology and 8 by histopathology. Acta Cytol 45:953–957

    Article  PubMed  CAS  Google Scholar 

  9. Tsang WYW, Chan JKC, Ng CS (1994) Kikuchi’s lymphadenitis: a morphologic analysis of 75 cases with special reference to unusual features. Am J Surg Pathol 18:219–231

    Article  PubMed  CAS  Google Scholar 

  10. Mohan A, Reddy MK, Phaneendra BV, Chandra A (2007) Aetiology of peripheral lymphadenopathy in adults: analysis of 1724 cases seen at a tertiary care teaching hospital in Southern India. Natl Med J India 20:78–80

    PubMed  Google Scholar 

  11. Jang YJ, Park KH, Seok HJ (2000) Management of Kikuchi’s disease using glucocorticoid. J laryngol Otol 114:709–711

    Article  PubMed  CAS  Google Scholar 

  12. Mahajan VK, Sharma NL (2005) Kikuchi-Fujimoto disease: immediate remission with ciprofloxacin. Int J Dermatol 43:370–372

    Article  Google Scholar 

Download references

Acknowledgments

I thank Dr.P·K. Rath MD(Path). Consulatant Pathologist, Doctors’ Diagnostic Centre, Trichy for his contribution from the Pathology Department.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aravind Ramkumar.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ramkumar, A. Kikuchi-Fujimoto Disease as a Differential Diagnosis for Cervical Lymphadenopathy in India: A Case Report and Review of Literature. Indian J Otolaryngol Head Neck Surg 63 (Suppl 1), 110–112 (2011). https://doi.org/10.1007/s12070-011-0218-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12070-011-0218-6

Keywords

Navigation