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Otolaryngology, although considered a surgical specialty, also covers many diseases that are not cured by surgery. These are treated medically and thus the otolaryngologist should have a good knowledge of drug treatments. It also entails ability to recognize, when an ENT symptom may be caused by one of the patient’s medications, particularly as this is easily remedied by changing the drug. Although most of us know the common drugs that can cause otological side effects, there are many others that we may not be aware of. Here we have tried to consolidate a list of some commonly used drugs having otological side effects.

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  1. Meville A (1984) Set and serendipity in the detection of drug hazards. Soc Sci Med 19:391–396

    Article  Google Scholar 

  2. Fausti SA et al (1992) High frequency audiometric monitoring for early detection of aminoglycoside ototoxicity. J Infect Dis 165(6):1026–1032

    Article  PubMed  CAS  Google Scholar 

  3. Hawkins JE (1976) Drug ototoxicity. In: Keidel WD, Neff WD (eds) Handbook of sensory physiology. Springer-Verlag, Berlin, pp 707–748

    Google Scholar 

  4. Ballantyne J (1973) Ototoxicity: a clinical review. Audiology 12:325

    Article  PubMed  CAS  Google Scholar 

  5. Brown RD, Feldman AM (1978) Pharmacology of hearing and ototoxicity. Ann Rev Pharmacol toxicol 18:233–252

    Article  CAS  Google Scholar 

  6. Bendush CL (1982) Ototoxicity: clinical considerations and comparative information. In: Whelton A, Neu HC (eds) The aminoglycosides, microbiology, clinical use and toxicology. Marcel Deckker, New York

    Google Scholar 

  7. Bergstrom L, Thompson PL (1984) Ototoxicity. In: Nourthern JL (ed) Hearing disorders, 2nd edn. Little Brown, Boston, pp 253–266

    Google Scholar 

  8. Johnson AH, Hamilton WH (1970) Kanamycin ototoxicity-possible potential by other drugs. South Med J 63:511–513

    Article  PubMed  CAS  Google Scholar 

  9. Fausti SA et al (1993) High frequency audiometric monitoring for early detection of cisplatin ototoxicity. Arch Otolaryngol Head Neck Surg 119(6):661–666

    PubMed  CAS  Google Scholar 

  10. Cary R, Clarke S, Delic J (1997) Effects of combined exposure to noise and toxic substances-critical review of literature. Ann Occup Hyg 41(4):455–465

    PubMed  CAS  Google Scholar 

  11. Lee CA, Mistry D, Uppal S, Coatesworth AP (2005) Otologic side effects of drugs. J Laryngol Otol 119:267–271

    PubMed  CAS  Google Scholar 

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Correspondence to Manisha Bisht.

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Bisht, M., Bist, S.S. Ototoxicity: The Hidden Menace. Indian J Otolaryngol Head Neck Surg 63, 255–259 (2011).

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