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Role of measurement of nasal mucociliary clearance by saccharine test as a yard stick of success of functional endoscopic sinus surgery

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Indian Journal of Otolaryngology and Head & Neck Surgery Aims and scope Submit manuscript

Abstract

Aim

The present study was done to establish normal nasal mucociliary clearance time (NMCT) in people of our region, study variations in NMCT in patients of chronic rhinosinusitis, to see change in NMCT after functional endoscopic sinus surgery (FESS) and to see whether saccharine test can be used as a yard stick of success of FESS.

Materials and methods

NMCT of 100 normal individual was measured twice to establish control value. Fourtythree patients of chronic rhinosinusitis were divided into polypoidal and non-polypoidal. Their symptom score, endoscopic appearance score, CT scan score and NMCT was measured preoperatively and postoperatively.

Results

NMCT in control group was 6.61 ± 0.84 minutes, in unilateral (u/l) polypoidal sinusitis 13.45 ± 2.07 minutes, in bilateral (b/l) polypoidal sinusitis 21.31 ± 0.76 minutes, u/l non-polypoidal sinusitis 9.54 ± 1.00 minutes and in b/l non-polypoidal sinusitis 11.34 ± 0.93 minutes. Linear relationship was seen between preoperative NMCT and preoperative symptom score, endoscopic appearance score, CT scan score. NMCT improved significantly after FESS.

Conclusion

NMCT measurement helps in selection of appropriate patients for surgery. It can be used as preoperative indicator of success of FESS.

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References

  1. Andersen I, Camner P, Jensen PL, Philipson K, Proctor DF (1974a) A comparison of nasal and tracheobronchial clearance. Arch Environ Health 29:290–293

    CAS  PubMed  Google Scholar 

  2. International Rhinosinusitis Advisory Board (1997) Infectious rhinosinusitis in adults: classification, etiology and management. Ear Nose Throat J (Suppl) 76:5–19

    Google Scholar 

  3. Lund VJ, Mackay IS (1993) Staging in rhinosinusitis. Rhinology 31:183–184

    CAS  PubMed  Google Scholar 

  4. Corbo GM, Foresi A, Bonfitto P, Mugnano A, Agabiti N, Cole PJ (1989) Measurement of nasal mucociliary clearance. Arch Dis Children 64(4):546–550

    Article  CAS  Google Scholar 

  5. Stringer SP, Stiles W, Slattery WH, Krumerman J, Parsons JT, Mendenhall WM, Cassisi NJ (1995) Nasal mucociliary clearance after radiation therapy. Laryngoscope 105(1): 380–382

    Article  CAS  PubMed  Google Scholar 

  6. Schuhl JF (1995) Nasal mucociliary clearance in perennial rhinitis. J Investig Allergol Clin Immunol 5(6):333–336

    CAS  PubMed  Google Scholar 

  7. Barry PW, Mason NP, O’Callaghan C (1997) Nasal mucociliary is impaired at altitude. Eur Respir J 10:35–37

    Article  CAS  PubMed  Google Scholar 

  8. Hafner B, Davris S, Riechelmann H, Mann WJ, Amedee RG (1997) Endonasal sinus surgery improves mucociliary transport in severe chronic sinusitis. Am J Rhinol 11(4): 271–274

    Article  CAS  PubMed  Google Scholar 

  9. Prior MJ, Schofield K, Boivin CM, Andersen P, Drake-Lee AB (1999) Assessment of mucociliary transport in patients with chronic mucoid rhinitis. Clin Otolaryngol 24(3): 242–246

    Article  CAS  PubMed  Google Scholar 

  10. Asai K, Haruna S, Otori N, Yanagi K, Fukami M, Moriyama H (2000) Saccharine test of maxillary sinus mucociliary function after endoscopic sinus surgery. Larygoscope 110(1):117–122

    Article  CAS  Google Scholar 

  11. Mahmut D, Celil U, Evren O, Davut A, Suleyman G (2006) Nasal mucociliary clearance in total laryngectomised patients. Eur Arch Otorhinolaryngol 263(12):1099–1104

    Article  Google Scholar 

  12. Golhar S (1986) Nasal mucus clearance. J Laryngol Otol 100:533–538

    Article  CAS  PubMed  Google Scholar 

  13. Birdi SM, Singh S, Singh A (1998) Mucociliary clearance in chronic sinusitis. Indian J Otolaryngol Head Neck Surg 50(1):15–19

    Article  Google Scholar 

  14. Ranga RK, Singh J, Gera A, Yadav J (2000) Nasal mucociliary clearance in adenotonsillar hypertrophy. Indian J Pediatrics 67(9):651–652

    Article  CAS  Google Scholar 

  15. Yadav J, Ranga RK, Singh J, Gathwala G (2001) Nasal mucociliary clearance in healthy children in a tropical country. Int J Pediat Otorhinolaryngol 57(1):21–24

    Article  CAS  Google Scholar 

  16. Ikeda K, Oshima T, Furukawa M, Katori Y, Shimomura A, Takasaka T, Maruoka S (1997) Restoration of the mucociliary clearance of the maxillary sinus after endoscopic sinus surgery. J Allergy Clin Immunol 99(1 Pt 1):48–52

    CAS  PubMed  Google Scholar 

  17. Kaluskar SK (1997) Pre and postoperative mucociliary clearance in functional endoscopic sinus surgery. Ear Nose Throat J 76(12):884–886

    CAS  PubMed  Google Scholar 

  18. Elwany S, Hisham M, Gamaee R (1998) The effect of endoscopic sinus surgery on mucociliary clearance in patients with chronic sinusitis. Eur Arch Otorhinolaryngol 255(10):511–514

    Article  CAS  PubMed  Google Scholar 

  19. Wang YF, Ye FC, Wang MS (2000) The effect of functional endoscopic sinus surgery on mucociliary clearance. Li Chuang Er Bi Yan Hou Ke Za Zhi 14(8):339–341

    CAS  Google Scholar 

  20. He G, Sun H, Zeng Q, Zhang S, Yang Y, Gu Y (2001) A comparative observation preoperatively and postoperatively of nasal mucosa in chronic sinusitis treated with endoscopic sinus surgery. Zhonghua Er Bi Yan Hou Ke Za Zhi 36(5):326–329

    CAS  PubMed  Google Scholar 

  21. Huang HM, Cheng JJ, Liu CM, Lin KN (2006) Mucosal healing and mucociliary transport change after endoscopic sinus surgery in children with chronic maxillary sinusitis. Int J Pediatr Otorhinolaryngol 70(8):1361–1367

    Article  PubMed  Google Scholar 

  22. Lund VJ, Holmstorm M, Scadding GK (1991) Functional endoscopic sinus surgery in the management of chronic rhinosinusitis. An objective assessment. J Laryngol Otol 105:832–835

    CAS  Google Scholar 

  23. Schnitkin B, May M, Shaprio A, Fucci M, Mester SJ (1993) Endoscopic sinus surgery: 4 year follow-up on the first 100 patients. Laryngoscope 103:1117–1120

    Google Scholar 

  24. Kaluskar SK (1997) Pre and postoperative mucociliary clearance in functional endoscopic surgery. Ear Nose Throat J 884-886

  25. Bhattacharyya T, Piccirillo J (1997) Relationship between patient-based description of sinusitis and paranasal sinus computed tomographic findings. Arch Otolaryngol Head Neck Surg 123:1189–1192

    CAS  PubMed  Google Scholar 

  26. Bradley DT, Kountakis SE (2005) Correlation between computed tomography scores and symptomatic improvement after endoscopic sinus surgery. Laryngoscope 115(3): 466–469

    Article  PubMed  Google Scholar 

  27. Bhattacharyya N (2006) Radiographic stages fails to predict symptom outcomes after endoscopic sinus surgery for chronic rhinosinusitis. Laryngoscope 116(1):18–22

    Article  PubMed  Google Scholar 

  28. Singh M, Chandra S (2006) Our experiences with FESS — a preliminary report. Asian J Ear Nose Throat 4(2):30–37

    Google Scholar 

  29. Gliklich RL, Metson R (1995) The health impact of chronic sinusitis in patients seeking otolaryngologic care. Otolaryngol Head Neck Surg 113:104–109

    Article  CAS  PubMed  Google Scholar 

  30. Benninger MS, Senoir B (1997) The development of the rhinosinusitis disability index. Arch Otolaryngol Head Neck Surg 123:1175–1179

    CAS  PubMed  Google Scholar 

  31. Gliklich R, Hilinski J (1995) Longitudinal sensitivity of generic and specific health measures in chronic rhinosinusitis. Quality Life Res 4:27–32

    Article  CAS  Google Scholar 

  32. Piccirillo J, Merritt J, Richards M (2002) Psycometric and clinmetric validity of the 20-item sino-nasal outcome test. Otolaryngol Head Neck Surg 126:41–47

    Article  PubMed  Google Scholar 

  33. Witsell D, Dolor R, Bolte J, et al. (2002) Exploring health related quality of life in patients with diseases of the ear, nose, and throat. Otolaryngol Head Neck Surg 126: 104–109

    Google Scholar 

  34. Senior B, Kennedy D (1998) Long-term results of FESS. Laryngoscope 108:151–156

    Article  CAS  PubMed  Google Scholar 

  35. Stammberger H, Posawetz W (1990) Results of endoscopic sinus surgery. Eur Arch Otorhinolaryngol 247:63–68

    Article  CAS  PubMed  Google Scholar 

  36. Wigand M, Hosemann W (1991) Results of endoscopic sinus surgery for the paranasal sinuses and anterior skull base. J Otolaryngol 20:385–390

    CAS  PubMed  Google Scholar 

  37. Shin S, Park J, Sohn J (1999) Clinical value of olfactory function tests after endoscopic sinus surgery: short term results. Am J Rhinol 12:63–66

    Article  Google Scholar 

  38. Mamikoglu B, Houser S, Corey J (2002) An interpretation method for objective assessment of nasal congestion with acoustic rhinometry. Laryngoscope 112:926–929

    Article  PubMed  Google Scholar 

  39. Doty R, Mishra A (2001) Olfaction and its alteration by nasal obstruction, rhinitis and rhinosinusitis. Laryngoscope 111:409–423

    Article  CAS  PubMed  Google Scholar 

  40. Stankiewicz JA, Chow JM (2002) Nasal endoscopy and the definition/diagnosis of chronic rhinosinusitis. Otolaryngol Head Neck Surg 126:623–627

    Article  PubMed  Google Scholar 

  41. Rosbe K, Jones K (1998) Usefulness of patient symptoms and nasal endoscopy in the diagnosis of chronic rhinosinusitis. Am J Rhinol 12:167–171

    Article  CAS  PubMed  Google Scholar 

  42. Bhattacharyya N (2004) Symptom outcome after endoscopic sinus surgery for chronic rhinosinusitis. Arch Otolaryngol Head Neck Surg 130:329–333

    Article  PubMed  Google Scholar 

  43. Damm M, Quante G, Jungehuelsing M, Stennert E (2002) Impact of functional endoscopic sinus surgery on symptom and quality of life in chronic rhinosinusitis. Laryngoscope 112:310–315

    Article  PubMed  Google Scholar 

  44. Benninger et al. (2003) Adult chronic rhinosinusitis: definition, diagnosis, epidemiology, and pathophysiology. Otolaryngol Head Neck Surg 129(3):S1–S32

    Article  PubMed  Google Scholar 

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Correspondence to Mangal Singh.

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Singh, M., Chandra, M., Gupta, S.C. et al. Role of measurement of nasal mucociliary clearance by saccharine test as a yard stick of success of functional endoscopic sinus surgery. Indian J Otolaryngol Head Neck Surg 62, 289–295 (2010). https://doi.org/10.1007/s12070-010-0074-9

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