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Is surgical vestibular ablation necessary in disabling peripheral vertigo?

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Abstract

The use of intratympanic gentamicin is an easily performed office procedure for the conservative treatment of the Meniere’s disease patient who has failed medical therapy. The procedure provides excellent control for the symptom of vertigo and is one of the most successful methods in the treatment of vertigo due to inner ear disorders. Surgical ablation is no longer necessary for adequate control of vestibular symptoms and that chemical ablation/alteration may replace the need for surgical vestibular ablation in cases of disabling Meniere’s disease and other inner ear causes for peripheral vertigo.

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References

  1. Glasscock ME, Kveton JF, Christiansen SG (1984) Middle fossa vestibular nerve section: an update. Otol Head Neck Surg 92:216–227

    Google Scholar 

  2. Fowler E (1948) Streptomycin treatment of vertigo. Trans Am Acad Ophthalmol Otolaryngol 52: 239–301

    Google Scholar 

  3. Schuknecht HF (1957) Ablation therapy in the management of Meniere’s disease. Acta Otolaruyngol (Stockh) 132: 1–42

    CAS  Google Scholar 

  4. Nedzelski JM, Chiong CM, Fradet G, et al (1993) Intratympanic gentamicin instillation as treatment of unilateral Meniere’s disease: update of an ongoing study. Am J Otol 14:278–282

    Article  PubMed  CAS  Google Scholar 

  5. Driscoll CLW, Kasperbauer JL, Facer GW, et al (1997) Low-dose intratympanic gentamicin and the treatment of Meniere’s disease: preliminary results. Laryngoscope 107: 83–89

    Article  PubMed  CAS  Google Scholar 

  6. Rauch SD, Oas JG (1997) Intratympanic gentamicin for treatment of intractable Meniere’s disease: a preliminary report. Laryngoscope 107:49–55

    Article  PubMed  CAS  Google Scholar 

  7. Corsten M, Marsan J, Schramm D, et al (1997) Treatment of intractable Meniere’s disease with intratympanic gentamicin: review of the University of Ottawa experience. J Otolaryngol 26:361–364

    PubMed  CAS  Google Scholar 

  8. McFeely WJ, Singleton GT, Rodriguez FJ et al. (1998) Intratympanic gentamicin treatment for Meniere’s disease. Otolaryngol Head Neck Surg 118(5): 589–596

    Article  PubMed  CAS  Google Scholar 

  9. Hirsch BE, Kamerer DB (1997) Intratympanic gentamicin therapy for Meniere’s disease. Am J Otol 18: 44–51

    Article  PubMed  CAS  Google Scholar 

  10. Minor LB (1999) Intratympanic gentamicin for control of vertigo in Meniere’s disease: vestibular signs that specify completion of therapy. Am J Otol 20: 209–219

    PubMed  CAS  Google Scholar 

  11. Laitakari K (1990) Intratympanic gentamicin in severe Meniere’s disease. Clin Otolaryngol 15:545–548

    Article  PubMed  CAS  Google Scholar 

  12. Murofushi T, Halmahyi GM, Yavor RA (1997) Intratympanic gentamicin in Meniere’s disease: results of therapy. Am J Otol 18:52–57

    PubMed  CAS  Google Scholar 

  13. Atlas J, Parnes LS (2003) Intratympanic gentamicin for intractable Meniere’s disease: 5-year follow-up. J Otolaryngol 32(5): 288–293

    Article  PubMed  Google Scholar 

  14. Odkvist LM (1989) Middle ear ototoxic treatment for inner ear disease. Acta Otolaryngol Suppl 457:83–86

    PubMed  CAS  Google Scholar 

  15. Toth AA, Parnes LS (1995) Intratympanic gentamicin therapy for Meniere’s disease: preliminary comparison of two regimens. J Otolaryngol 24:340–344

    PubMed  CAS  Google Scholar 

  16. Silverstein H, Rosenberg S, Arruda J, et al (1997) Surgical ablation of the vestibular system in the treatment of Meniere’s disease. Otolaryngol Clin N Am 30:1075–1095

    CAS  Google Scholar 

  17. Youssef TF, Poe DS (1998) Intratympanic gentamicin injection for the treatment of Meniere’s disease. Am J Otol 19: 435–442

    PubMed  CAS  Google Scholar 

  18. Blakely BW (2000) Update on intratympanic gentamicin for Meniere’s disease. Laryngoscope 110:236–240

    Article  Google Scholar 

  19. Diamond C, O’Connell DA, Hornig JD, et al (2003) Systematic review of intratympanic gentamicin in Meniere’s disease. J Otolaryngol 32(6):351–361

    Article  PubMed  Google Scholar 

  20. Wu IC, Minor LB (2003) Long-term hearing outcome in patients receiving intratympanic gentamicin for Meniere’s disease. Laryngoscope 113(5): 815–820

    Article  PubMed  CAS  Google Scholar 

  21. Monsell EM, Cass SP, Rybak LP, Nedzelski JM (2001) Chemical treatment of the labyrinth. In Brackmann DE, Shelton C ed. Otologic surgery. W.B. Saunders Company, Philadelphia. 413–421

    Google Scholar 

  22. Harner SG, Driscoll CLW, Facer GW, et al (2001) Longterm follow-up of transtympanic gentamicin for Meniere’s syndrome. Otol Neurotol 22:210–214

    Article  PubMed  CAS  Google Scholar 

  23. Brantberg K, Bergenius J, Tribukait A (1996) Gentamicin treatment in peripheral vestibular disorders other than Meniere’s disease. ORL J Otorhinolaryngol Relat Spec 58: 277–279

    PubMed  CAS  Google Scholar 

  24. Langman AW, Kemink JL, Graham MD (1990) Titration streptomycin therapy for bilateral Meniere’s disease. Follow-up report. Ann Otol Rhinol Laryngol 99(11):923–926

    PubMed  CAS  Google Scholar 

  25. Balyan FR, Taibah A, De Donato G, et al (1998) Titration streptomycin therapy in Meniere’s disease: long-term results. Otolaryngol Head Neck Surg 118(2):261–226

    Article  PubMed  CAS  Google Scholar 

  26. Pyykko I, Ishizaki H, Kassinen S, et al (1994) Intratympanic gentamicin in bilateral Meniere’s disease. Otolaryngol Head Neck Surg 110(2):162–167

    PubMed  CAS  Google Scholar 

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Mahadevaiah, A., Parikh, B. Is surgical vestibular ablation necessary in disabling peripheral vertigo?. Indian J Otolaryngol Head Neck S 60, 30–34 (2008). https://doi.org/10.1007/s12070-008-0010-4

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