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Analysis of preoperative and postoperative blood gas indices and airflow dynamics with tracheal stenosis undergoing tracheal reconstruction

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Abstract

Prolonged ventilation remains the most common cause of tracheal stenosis. Tracheal reconstruction is the gold standard treatment in these cases. The success of surgery is based on results of the pulmonary function test (PFT) which relies on patients’ performance and their cooperation. The objective of the study was to investigate the impact of tracheal reconstruction in cases of tracheal stenosis on blood gas indices as well as airflow indices and whether arterial blood gas (ABG) can be a better surrogate of adequacy of tracheal reconstruction. This was a retrospective observational study of 61 patients with tracheal stenosis between the ages of 21 and 65 years who underwent tracheal reconstruction. The preoperative and postoperative values of various blood gas indices like partial pressure of oxygen (pO2), partial pressure of carbon dioxide (pCO2), and potential of hydrogen (pH) and airflow indices like forced expiratory volume in 1 s (FEV1) and peak expiratory flow (PEF) were evaluated and found that all the parameters showed significant improvement after tracheal reconstruction with P < 0.0001. Tracheal reconstruction resulted in improvement of oxygenation and airflow parameters which led to relief of symptoms. Hence, ABG can be used as a surrogate marker for denoting the success of the surgery.

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Abbreviations

pO2 :

Partial pressure of oxygen

pCO2 :

Partial pressure of carbon dioxide

FEV1:

Forced expiratory volume in 1 s

pH:

Potential of hydrogen

COPD:

Chronic obstructive pulmonary disease

BMI:

Body mass index

ETS:

Excised tracheal stenosis

CPB:

Cardiopulmonary bypass

ABG:

Arterial blood gas

ET:

Endotracheal tube

References

  1. Farzanegan R, Farzanegan B, Zangi M, Golestani EM, Noorbakhsh S, Doozandeh TN, et al. Incidence rate of post-intubation tracheal stenosis in patients admitted to five intensive care units in Iran. Iran Red Crescent Med J. 2016;18: e37574. https://doi.org/10.5812/ircmj.37574.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Biswas A, Mehta HJ, Jantz MA. A 62-year-old woman with refractory wheezing. Chest. 2018;153:e57–62. https://doi.org/10.1016/j.chest.2017.08.019.

    Article  PubMed  Google Scholar 

  3. Nair S, Nilakantan A, Sood A, Gupta A, Gupta A. Challenges in the management of laryngeal stenosis. Indian J Otolaryngol Head Neck Surg. 2016;68:294–9. https://doi.org/10.1007/s12070-015-0936-2.

    Article  PubMed  Google Scholar 

  4. Al-Qadi MO, Artenstein AW, Braman SS. The “forgotten zone”: acquired disorders of the trachea in adults. Respir Med. 2013;107:1301–13. https://doi.org/10.1016/j.rmed.2013.03.017.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Shepard JO, Flores EJ, Abbott GF. Imaging of the trachea. Ann Cardiothorac Surg. 2018;7:197–209. https://doi.org/10.21037/acs.2018.03.09.

    Article  PubMed  PubMed Central  Google Scholar 

  6. Fernando HC, Dekeratry D, Downie G, Finley D, Sullivan V, Sarkar S, et al. Feasibility of spray cryotherapy and balloon dilation for non-malignant strictures of the airway. Eur J Cardiothorac Surg. 2011;40:1177–80. https://doi.org/10.1016/j.ejcts.2011.02.062.

    Article  PubMed  Google Scholar 

  7. Motus IY, Konstantinova OS, Giss NA. Cicatricial tracheal stenosis. Is prevention possible? A single-region experience. Khirurgiia (Mosk). 2023;6:42–7. https://doi.org/10.17116/hirurgia202306142.

    Article  Google Scholar 

  8. Bacon JL, Patterson CM, Madden BP. Indications and interventional options for non- resectable tracheal stenosis. J Thorac Dis. 2014;6:258–70. https://doi.org/10.3978/j.issn.2072-1439.2013.11.08.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Alrabiah A, Almohanna S, Aljasser A, Zakzouk A, Habib SS, Almohizea M, et al. Utility of spirometry values for evaluating tracheal stenosis patients before and after balloon dilation. Ear Nose Throat J. 2022;101:NP62–NP7. https://doi.org/10.1177/0145561320936968.

    Article  Google Scholar 

  10. Pinto J, Chambel B, Freitas C, Conceição M, Morais A, Fernandes G, et al. Spirometry as an integral part of benign tracheal stenosis management. Eur Respir J. 2020;56:2844. https://doi.org/10.1183/13993003.congress-2020.2844.

    Article  Google Scholar 

  11. Abdullah A, Alrabiah A, Habib SS, Aljathlany Y, Aljasser A, Bukhari M, et al. The value of spirometry in subglottic stenosis. Ear Nose Throat J. 2019;98:98–101. https://doi.org/10.1177/0145561318823309.

    Article  PubMed  Google Scholar 

  12. Vergnon JM, Costes F, Bayon MC, Emonot A. Efficacy of tracheal and bronchial stent placement on respiratory functional tests. Chest. 1995;107:741–6. https://doi.org/10.1378/chest.107.3.741.

    Article  PubMed  CAS  Google Scholar 

  13. Kandaswamy C, Bird G, Gill N, Math E, Vempilly JJ. Severe tracheomalacia in the ICU: identification of diagnostic criteria and risk factor analysis from a case control study. Respir Care. 2013;58:340–7. https://doi.org/10.4187/respcare.01866.

    Article  PubMed  Google Scholar 

  14. Maresh A, Preciado DA, O’Connell AP, Zalzal GH. A comparative analysis of open surgery vs endoscopic balloon dilation for pediatric subglottic stenosis. JAMA Otolaryngol Head Neck Surg. 2014;140:901–5. https://doi.org/10.1001/jamaoto.2014.1742.

    Article  PubMed  Google Scholar 

  15. Song SA, Sandhu G, Franco RA Jr. Should we routinely use pulmonary function testing in the management of subglottic stenosis? Laryngoscope. 2021;131:245–7. https://doi.org/10.1002/lary.28678.

    Article  PubMed  Google Scholar 

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Correspondence to Sandeep Kumar Kar.

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Ghosh, K., Kar, S.K. & Dammalapati, P.K. Analysis of preoperative and postoperative blood gas indices and airflow dynamics with tracheal stenosis undergoing tracheal reconstruction. Indian J Thorac Cardiovasc Surg (2024). https://doi.org/10.1007/s12055-024-01694-w

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