Skip to main content

Advertisement

Log in

Solitary endobronchial plasmacytoma—a rare differential of an endobronchial mass

  • Case report
  • Published:
Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Diagnostic dilemma, owing to the inconclusiveness of biopsy results, often leaves us with limited options to offer to the patients upfront, amongst the various armamentarium available. We hereby report a rare case of extramedullary plasmacytoma, whose diagnosis was established only on the final histopathology report with the aid of immunohistochemistry. A 50-year-old gentleman presented to our outpatient setup with computed tomography suggestive of a well-defined endobronchial mass occupying the left lower lobe bronchus. However, bronchoscopy and computed tomography–guided biopsies were inconclusive. After a routine metastatic workup, the patient underwent a left lower lobectomy following a provisional diagnosis of carcinoid on the frozen section. The final histopathology was solitary endobronchial plasmacytoma. Postoperative myeloma workup was within normal limits and the patient is doing well and disease free at 8 months of follow-up. This rare differential needs to be kept in mind while evaluating a case of well-defined endobronchial growth.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

Data Availability

Data supporting this study are included within the article.

Abbreviations

CT :

Computed tomography

IHC :

Immunohistochemistry

EMP :

Extramedullary plasmacytoma

SEP :

Solitary endobronchial plasmacytoma

PET-CT :

Positron emission tomography-computed tomography

Nd-Yag :

Neodymium-doped yttrium aluminum garnet

MGUS :

Monoclonal gammopathy of undetermined significance

MM :

Multiple myeloma

References

  1. Batsakis JG, Medeiros JL, Luna MA, El-Naggar AK. Plasma cell dyscrasias of the head and neck. Ann Diagn Pathol. 2002;6:129–40.

    Article  PubMed  Google Scholar 

  2. Iqbal QUA, Majid HJ. Plasmacytoma. [Updated 2022 Aug 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK573076/. Accessed 3 May 2023

  3. Meyer HJ, Ullrich S, Hamerla G, Surov A. Extramedullary plasmacytoma. Rofo. 2018;190:1006–9.

    Article  PubMed  Google Scholar 

  4. Edelstein E, Gal AA, Mann KP, Miller JI, Mansour KA. Primary solitary endobronchial plasmacytoma. Ann Thorac Surg. 2004;78:1448–9.

    Article  PubMed  Google Scholar 

  5. Brackett LE, Myers JR, Sherman CB. Laser treatment of endobronchial extramedullary plasmacytoma. Chest. 1994;106:1276–7.

    Article  CAS  PubMed  Google Scholar 

  6. Terzi A, Furlan G, Zannoni M, Adovasio A, Gorla A. Endobronchial extramedullary plasmacytoma. Report of one case. Lung Cancer. 1996;16:95–100.

    Article  CAS  PubMed  Google Scholar 

  7. Park JI, Lee YY, Lee SS, Ahn JH. A rare case of primary solitary endobronchial plasmacytoma. Thorac Cancer. 2021;12:958–61. https://doi.org/10.1111/1759-7714.13853.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Joseph G, Pandit M, Korfhage L. Primary pulmonary plasmacytoma. Cancer. 1993;71:721–4. https://doi.org/10.1002/1097-0142(19930201)71:3<721::aid-cncr2820710311>3.0.co;2-u .

  9. Tenholder MF, Scialla SJ, Weisbaum G. Endobronchial metastatic plasmacytoma. Cancer. 1982;49:1465–8.

    Article  CAS  PubMed  Google Scholar 

  10. Wiltshaw E. The natural history of extramedullary plasmacytoma and its relation to solitary myeloma of bone and myelomatosis. Medicine. 1976;55:217–38.

    Article  CAS  PubMed  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohit Sharma.

Ethics declarations

Ethical approval

Not required being a case report.

Informed consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given consent for his images and other clinical information to be reported in the journal. The patient understands that his name and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Statement of human and animal rights

Not required as no experimental procedure was carried out and no animals involved.

Conflict of interest

None.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kapur, K., Sharma, M., Puj, K. et al. Solitary endobronchial plasmacytoma—a rare differential of an endobronchial mass. Indian J Thorac Cardiovasc Surg 39, 629–631 (2023). https://doi.org/10.1007/s12055-023-01557-w

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12055-023-01557-w

Keywords

Navigation