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Long-term experience with valve-sparing root reimplantation surgery in tricuspid aortic valve

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Indian Journal of Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Objective

To analyze our long-term experience with valve-sparing reimplantation technique in treating aortic root aneurysm, aortic regurgitation, and aortic dissection in patients with tricuspid aortic valve.

Methods

Between March 1998 and October 2018, 303 consecutive patients underwent valve-sparing reimplantation in our institution. The mean age of this cohort was 52.9 ± 15 years. Time to event analysis was performed with the Kaplan-Meier method. Risk of death, reoperation, and aortic regurgitation (AR) recurrence were analyzed using the cox-regression method.

Results

In-hospital mortality was 1% (n = 3) of which two were admitted for acute aortic dissection. Median follow-up was 5.81 years ([IQR]: 2.8–10 years). Thirty-nine patients (14.4%) died during follow-up. At 5 and 10 years, overall survival was 92 ± 2%and 75 ± 4.9%, respectively. Seventeen patients required late aortic valve reoperation. Freedom from valve reoperation was 95 ± 2% and 90 ± 3%. Freedom from AR > 2+ and AR > 1+ at 10 years was 91 ± 4% and 71.5 ± 4.6%, respectively. Significant multivariate predictors of death included age, New York Heart Association dyspnea class (NYHA), type A acute dissection (TAAD), and preoperative left ventricular end-diastolic diameter (LVEDD). Significant multivariate predictors of AR recurrence included indication for surgery, previous cardiac surgery, and presence of preoperative AR. Freedom from events like major bleeding, thromboembolic events, and infective endocarditis at 10 years were 97%, 98%, and 96%, respectively.

Conclusions

Aortic valve-sparing with the reimplantation technique has been performed for over two decades in our institution, and the results in patients with tricuspid aortic valve (TAV) are excellent in terms of survival and freedom from valve-related adverse outcomes including valve reoperation. These results continue supporting the use of valve sparing root replacement using the reimplantation technique (VSRR) in patients with aortic aneurysm, irrespective of whether they have preoperative AR or not. VSRR is safe, durable, and reproducible, but further follow-up, well into the second decade is still necessary.

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Authors and Affiliations

  1. Pôle de Recherche Cardiovasculaire, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain and Division of Cardiothoracic and Vascular Surgery, Cliniques Universitaires Saint-Luc, Brussels, Belgium

    Saadallah Tamer, Stefano Mastrobuoni, Gaby Aphram, Emiliano Navarra, Alain Poncelet, Philippe Noirhomme, Parla Astarci, Gebrine El Khoury & Laurent de Kerchove

  2. Division of Anesthesiologyy, Cliniques Universitaires Saint-Luc, Brussels, Belgium

    Mona Momeni

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  1. Saadallah Tamer
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  2. Stefano Mastrobuoni
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  3. Mona Momeni
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  4. Gaby Aphram
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  10. Laurent de Kerchove
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Correspondence to Saadallah Tamer.

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This observational study was approved by the Review Ethics Board of Université Catholique de Louvain, and a waiver of consent was obtained.

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Tamer, S., Mastrobuoni, S., Momeni, M. et al. Long-term experience with valve-sparing root reimplantation surgery in tricuspid aortic valve. Indian J Thorac Cardiovasc Surg 36 (Suppl 1), 71–80 (2020). https://doi.org/10.1007/s12055-019-00842-x

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  • DOI: https://doi.org/10.1007/s12055-019-00842-x

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