Abstract
In order to eliminate the complication of bleeding following open heart surgery we studied a group of patients in whom the pre-operative international normalized ratio (INR) was estimated. Those with INR less than 2 had less bleeding. Those with INR between 2 nd 2.5 need individualized management and may require aprotinin.
This is a preview of subscription content, log in via an institution to check access.
References
Rapaport S. Preoperative hemostatic evaluation, which test if any? Blood 1983; 61: 229–31.
Gravlee GP, Arora S, Lavender SW, et al. Predictive value of blood clotting tests in cardiac surgical patients. Ann Thorac Surg 1994; 58: 216–21.
Czer LS, Bateman TM, Gray RJ, et al. Treatment of severe platelet dysfunction and hemorrhage after cardiopulmonary bypass; reduction in blood products usage with desmopressin. J. Am Coll Crdiol 1987; 9: 1139–47.
Salzman EW, Weinstein ML, Weintraub RM, et al. Treatment with desmopressin acetate to decrease blood loss after cardiac surgery. N Engl J Med 1986; 314: 1402–06.
Bidstrup BP, Royston D, Sapsford RN, et al. Decrease in blood loss and blood use after CPB with high dose aprotinin (Trasylol). J Thorac Cardiovasc Surg 1989; 97: 364–72.
Giordano GF, Goldman DS, Mammana RB. Intraoperative autotransfusion in cardiac operation: effect on intraoperative and post-operative transfusion requirements. J Thorac Cardiovasc Surg 1988; 96: 382–86.
Rousou J, Gonzalez-Lavin L, Cosgrove D. Randomized clinical trial of fibrin sealent in patients undergoing resternotomy or reoperation after cardiac operation. JTCV 1989; 97: 194–203.
Kirklin JW, Barratt Boyes BG. Post-operative care. In Kirklin JW, Barratt Boyes BG, 3rd edition Cardiac Surgery; Churchill Livingston, New York: Page 226–27.
Ratnatunga CP, Rees GM, Kovacs IB. Preoperative hemoststaic activity and excessive bleeding after CPB. Ann Thorac Surg 1991; 52: 250–57.
Bick RL. Alterations of hemostasis associated with CPB: pathopysiology, prevention, diagnosis and management. Semim Thromb Hemostas 1976; 3: 59–82.
Leichtmen DA, Freidman BA. The hemorrhagic complications of open heart surgery. CRC Crit Reo Clin Lab Sci 1977; 7: 239–54.
Loeliger EA, Besselaar AMHP, Lewis SM. Relability and clinical impact of the normalization of the prothrombin times in oral anticoagulation control. Throm & Hemostsis 1985; 53: 148–54.
Kaplan EB, Sheiner LB, Boeckmann AJ, et al. The usefulness of preoperative laboratory testing. JAMA 1985; 253: 3576–81.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kumar, P., Chikkatur, R., Kandhachar, P. et al. Preoperative international normalised ratio (INR) and bleeding during open-heart procedure. Indian J Thorac Cardiovasc Surg 20, 132–134 (2004). https://doi.org/10.1007/s12055-004-0064-1
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/s12055-004-0064-1