Skip to main content
Log in

Deep Eutectic Solvents

  • General Article
  • Published:
Resonance Aims and scope Submit manuscript

Abstract

Solvents play a crucial role in promoting chemical reactions. They are essential for transporting reactants and energy transfer. Mostly volatile organic compounds (VOCs) are used as solvents. While volatile, such solvents are flammable, environmentally hazardous, highly polluting, toxic, derived from depleting petroleum reserves, and unsustainable, and hence not considered ‘green’. Society views VOCs as a necessary evil. The fortuitous discovery of deep eutectic solvents (DESs) has changed the bleak scenario. DESs allow the sustainable conduct of chemical reactions. Site-specific DESs meet most of the requirements to be called green solvents/designer solvents/solvents of the future. This preliminary review will high-light their discovery, characteristics, properties, and applications. Through this review, we intend to introduce the concept of DESs to the novice and kindle interest in this fast-emerging field of research.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Suggested Reading

  1. H. Boerhave, Elementa Chemiae (in Latin), Vols.1 and 2, Leiden, 1732

  2. H. Boerhave, Historia Plantarum quae in Horto Academico Lugduni-Batavorum Crescent (in Latin) Vols.1 and 2, Amsterdam, 1738.

  3. G. Wypych (ed), Handbook of Solvents, ChemTec Publishing, Toronto–New York, 2001.

    Google Scholar 

  4. J. H Clark, A. Hunt, C. Topi, G. Paggiola, J. Sherwood, Sustainable Solvents: Perspectives from Research, Business and International Policy, Royal Society of Chemistry, 2017.

  5. D. R MacFarlane, M. Kar, J. M Pringle, Fundamentals of Ionic Liquids: From Chemistry to Applications, John Wiley & Sons, 2017.

  6. P. C Rây, J. N Rakshit, CLXVIL-Nitrites of the alkylammonium bases: Ethylammonium nitrite, dimethylammonium nitrite, and trimethylammonium nitrite, J. Chem. Soc. Trans., 99, pp.1470–1475, 1911

    Article  Google Scholar 

  7. R. Ghosh, Discovery of room temperature ionic liquid, Resonance, Vol.26, No.2, pp.241–244, 2021.

    Article  Google Scholar 

  8. P. Walden, Über die Molekulargrösse und Elektrische Leitfähigkeit Einiger Geschmolzener Salze, Bull. Acad. Imper. Sci., (St Petersburg) 8, pp.405–422, 1914

    Google Scholar 

  9. T. Welton, Ionic liquids: A brief history, Biophysical Reviews, 10, pp.691–706, 2018.

    Article  Google Scholar 

  10. J. S. Wilkes, M. J. Zaworotko, Air and water stable 1-ethyl-3-methylimidazolium based ionic liquids, J. Chem. Soc. Chem. Com., No.13, pp.965–967, 1992.

  11. D. J. Ramón, G. Guillena, Deep Eutectic Solvents: Synthesis, Properties, and Applications, John Wiley & Sons, 2020

  12. V. Hessel, N. N. Tran, M. R. Asrami, Q. D. Tran, N. V. D. Long, M. Escribà-Gelonch, J. O. Tejada, S. Linke, K. Sundmacher, Sustainability of green solvents—Review and perspective, Green Chemistry, 24, pp.410–437, 2022.

    Article  Google Scholar 

  13. A. P. Abbott, D. L. Davies, G. Capper, R. K. Rasheed, V. Tambyrajah, Ionic Liquids and Their Use as Solvents, WO2002026701A2, 2002.

  14. D. O. Abranches, J. A. Coutinho, Type V deep eutectic solvents: Design and applications, Current Opinion in Green and Sustainable Chemistry, p.100612, 2022.

  15. A. P. Abbott, D. Boothby, G. Capper, D. L. Davies, R. K. Rasheed, Deep eutectic solvents formed between choline chloride and carboxylic acids: Versatile alternatives to ionic liquids, J. Am. Chem. Soc., 126, pp.9142–9147, 2004.

    Article  Google Scholar 

  16. https://patents.google.com/.

Download references

Acknowledgment

I thank Pondicherry University, Vasishta Pharma, and Teadus Pharma for their support.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to H. Surya Prakash Rao.

Additional information

Dr H. Surya Prakash Rao taught and conducted research in organic chemistry for 30 years at Pondicherry University, from where he superannuated in 2018. Subsequently, he served at Sharda University and Vasista Pharma. Presently, he is Scientific Advisor to Teadus Pharma Pvt. Ltd. in Hyderabad. He has served the Indian Academy of Sciences as an editorial board member for the Journal of Chemical Sciences for over ten years.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Rao, H.S.P. Deep Eutectic Solvents. Reson 28, 1865–1874 (2023). https://doi.org/10.1007/s12045-023-1724-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12045-023-1724-z

Keywords

Navigation