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How Enzyme Inhibition Works!

An Insight into the Mechanism of Inhibition of α-Amylase by Copper Sulphate

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Abstract

In this article, we establish the mechanism of inhibitory action of copper sulphate pentahydrate on α-amylases. This experiment will give insight to the students about the mode of action of α-amylase, the role of calcium ions in the activity of α-amylase and the possible mechanism of enzyme inhibition.

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Authors and Affiliations

  1. Sri Venkateswara College, University of Delhi, New Delhi, 110 021, India

    Sharda Pasricha & Pragya Gahlot

Authors
  1. Sharda Pasricha
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  2. Pragya Gahlot
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Corresponding authors

Correspondence to Sharda Pasricha or Pragya Gahlot.

Additional information

Sharda Pasricha is an Associate Professor in the Department of Chemistry, Sri Venkateswara College Delhi. Her research interests include natural product chemistry, green chemistry, and medicinal chemistry, focusing on heterocycles, synthesis, and heterogeneous catalysts in organic transformations.

Pragya Gahlot is an Assistant Professor at Sri Venkateswara College, Delhi. Her research interests include molecular docking, drug design, and QSAR.

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Pasricha, S., Gahlot, P. How Enzyme Inhibition Works!. Reson 27, 825–834 (2022). https://doi.org/10.1007/s12045-022-1375-5

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  • DOI: https://doi.org/10.1007/s12045-022-1375-5

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