Switches in the Brain?

A Potential Mechanism for Long-term Memory Storage


We forget often. But some memories last a lifetime. This means that our brain is capable of protecting memories for years. This is a remarkable feat given that the biochemical hardware involved in creating new memories is a hostile place for its storage. What are the challenges involved? And what type of biochemical mechanisms may overcome them? This article explores a major hypothesis that molecular switches may be behind our remarkable ability to remember for a lifetime.

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I’d like to thank Dr Somya Mani, Bhanu Priya and Dr Mukund Thattai for helpful suggestions on the manuscript.

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Correspondence to Dilawar Singh.

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Dilawar Singh is currently a graduate student at National Center for Biological Sciences (NCBS), Bengaluru. His hobby is to convince people to move to open-source softwares to live happily ever after.

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Singh, D. Switches in the Brain?. Reson 24, 963–975 (2019). https://doi.org/10.1007/s12045-019-0863-8

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