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G N Ramachandran’s contributions to medical imaging

Substance from shadows

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Abstract

G N Ramachandran made several remarkable contributions to biophysics and structural biology over the course of his celebrated career. In a pair of seminal papers in 1971, he also laid the foundation for the technique of ‘Projection Reconstruction’ that has come to revolutionize medical imaging. It is now routinely employed in modern CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) scans. In this article, we review the salient features of this technique, that allows the ‘reconstruction of an object from its shadows’.

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Authors and Affiliations

  1. Department of Physics and NMR Research Centre, Indian Institute of Science, Bengaluru, 560 012, India

    Anil Kumar

  2. Research Lab of Electronics Massachusetts, Institute of Technology, Cambridge, USA

    Ashok Ajoy

Authors
  1. Anil Kumar
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  2. Ashok Ajoy
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Correspondence to Anil Kumar.

Additional information

(left) Anil Kumar, Department of Physics and NMR Research Centre, IISc, Bengaluru, is currently National Academy of Sciences India (NASI) Senior Scientist Platinum Jubilee Fellow. His area of research is ‘NMR technique development’ with applications to bio-molecular structure determination, MRI, quantum information processing and quantum computing by NMR.

(right) Ashok Ajoy is a graduate student in the Research Lab of Electronics, MIT, Cambridge. His research involves developing techniques for nanoscale MRI using spin defects in diamond, and work in the area of quantum assisted metrology, simulation and control.

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Kumar, A., Ajoy, A. G N Ramachandran’s contributions to medical imaging. Reson 21, 741–747 (2016). https://doi.org/10.1007/s12045-016-0378-5

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  • DOI: https://doi.org/10.1007/s12045-016-0378-5

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