This is a preview of subscription content, log in via an institution to check access.
References
Clemens K. E., Churchill G., Bhatt N., Richardson K. and Noonan F. P. 2000 Genetic control of susceptibility to UV-induced immunosuppression by interacting quantitative trait loci. Genes Immun. 1, 251–259.
MacDonald I. L. 2014 Numerical maximisation of likelihood: A neglected alternative to EM? Int. Stat. Rev. 82, 296–308.
Ott J. 1991 Analysis of human genetic linkage. Johns Hopkins University Press, Baltimore, USA, revised edition.
R Core Team 2014 R: a language and environment for statistical computing, version 3.1.2. R Foundation for Statistical Computing, Vienna, Austria.
Zhou Y., Shi N.-Z., Fung W.-K. and Guo J. 2008 Maximum likelihood estimates of two-locus recombination fractions under some natural inequality restrictions. BMC Genet. 9.
Zhou Y., Ma W., Sheng X. and Wang H. 2011 A new strategy for estimating two-locus recombination fractions under some natural inequality restrictions. J. Genet. 90, 275–282.
Acknowledgements
The editor, the referee and Dr Miguel Lacerda are thanked for their very helpful suggestions.
Author information
Authors and Affiliations
Corresponding author
Additional information
[MacDonald I. L. and Nkalashe P. 2015 A simple route to maximum-likelihood estimates of two-locus recombination fractions under inequality restrictions. J. Genet. 94, xx–xx]
Rights and permissions
About this article
Cite this article
MACDONALD, I.L., NKALASHE, P. A simple route to maximum-likelihood estimates of two-locus recombination fractions under inequality restrictions. J Genet 94, 479–481 (2015). https://doi.org/10.1007/s12041-015-0536-7
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12041-015-0536-7