The genetic factors influencing the development of trichotillomania
- 298 Downloads
Trichotillomania (TTM), an obsessive–compulsive spectrum disorder (OCSD), is a psychiatric condition characterized by repetitive hair pulling. Evidence from family and twin studies suggest a heritable link of TTM. Functional polymorphisms in genes involved in neuronal pathways might influence the susceptibility to TTM. This review is an attempt to compile the genetic factors reported to modify the development of TTM.
Keywordstrichotillomania familial genes polymorphism
Unable to display preview. Download preview PDF.
- American Psychiatric Association 1994 Diagnostic and statistical manual of mental disorders, 4th edition. American Psychiatric Association, Washington D.C., USA.Google Scholar
- American Psychiatric Association 2000 DSM-IV-TR. American Psychiatric Association, Washington D.C., USA.Google Scholar
- Bienvenu O. J., Wang Y., Shugart Y. Y., Welch J. M., Grados M. A., Fyer A. J. et al. 2009 Sapap3 and pathological grooming in humans: results from the OCD collaborative genetics study. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150, 710–720.Google Scholar
- Novak C. E., Keuthen N. J., Stewart S. E. and Pauls D. L. 2009 A twin concordance study of trichotillomania. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150, 944–949.Google Scholar