Skip to main content
Log in

A national survey on the allelic, genotypic, and haplotypic distribution of PRNP insertion and deletion polymorphisms in Korean cattle

  • Research Note
  • Published:
Journal of Genetics Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Belt P. B., Muileman I. H., Schreuder B. E., Bos-de Ruijter J., Gielkens A. L. and Smits M. A. 1995 Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie. J. Gen. Virol. 76, 509–517.

    Article  PubMed  CAS  Google Scholar 

  • Billinis C., Panagiotidis C. H., Psychas V., Argyroudis S., Nicolaou A., Leontides S. et al. 2002 Prion protein gene polymorphisms in natural goat scrapie. J. Gen. Virol. 83, 713–721.

    PubMed  CAS  Google Scholar 

  • Chiesa R., Drisaldi B. E., Quaglio A., Migheli P., Piccardo P., Ghetti B. and Harris D. A. 2000 Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation. Proc. Natl. Acad. Sci. USA 97, 5574–5579.

    Article  PubMed  CAS  Google Scholar 

  • Goldmann W. 2008 PrP genetics in ruminant transmissible spongiform encephalopathies. Vet. Res. 39, 30.

    Article  PubMed  CAS  Google Scholar 

  • Goldmann W., Hunter N., Martin T., Dawson M. and Hope J. 1991 Different forms of the bovine PrP gene have five or six copies of a short, G-C-rich element within the protein-coding exon. J. Gen. Virol. 72, 201–204.

    Article  PubMed  CAS  Google Scholar 

  • Hill A. F., Desbruslais M., Joiner D., Sidle K. C., Gowland I., Collinge J. et al. 1997 The same prion strain causes vCJD and BSE. Nature 389, 448–450.

    Article  PubMed  CAS  Google Scholar 

  • Jeong B. H., Lee Y. J., Kim N. H., Carp R. I. and Kim Y. S. 2006 Genotype distribution of the prion protein gene promoter polymorphisms in Korean cattle. Genome 49, 1539–1544.

    Article  PubMed  CAS  Google Scholar 

  • Kim Y., Lee J. and Lee C. 2008 In sillico comparative analysis of DNA and amino acid sequences for prion protein gene. Transboundary Emerg. Dis. 55, 105–114.

    Article  CAS  Google Scholar 

  • O’Rourke K. I., Spraker T. R., Hamburg L. K., Besser T. E., Brayton K. A. and Knowles D. P. 2004 Polymorphisms in the prion precursor functional gene but not the pseudogene are associated with susceptibility to chronic wasting disease in white-tailed deer. J. Gen. Virol. 85, 1339–1346.

    Article  PubMed  CAS  Google Scholar 

  • Owen F., Poulter M., Collinge J., Leach M., Lofthouse R., Crow T. J. and Harding A. E. 1992 A dementing illness associated with a novel insertion in the prion protein gene. Brain Res. Mol. Brain Res. 13, 155–157.

    Article  PubMed  CAS  Google Scholar 

  • Palmer M. S., Dryden A. J., Hughes J. T. and Collinge J. 1991 Homozygous prion protein genotype predisposes to sporadic Creutzfeldt-Jakob disease. Nature 352, 340–342.

    Article  PubMed  CAS  Google Scholar 

  • Premzl M. and Gamulin V. 2007 Comparative genomic analysis of prion genes. BMC Genomics 8, 1.

    Article  PubMed  CAS  Google Scholar 

  • Premzl M., Bozic P. and Gamulin V. 2000 PRNP octarepeat allele genotype frequencies among the modern and rare cattle breeds in Croatia. Anim. Genet. 31, 408–409.

    Article  PubMed  CAS  Google Scholar 

  • Prusiner S. B. 1991 Molecular biology of prion diseases. Science 252, 1515–1522.

    Article  PubMed  CAS  Google Scholar 

  • Sander P., Hamann H., Drogemuller C., Kashkevich K., Schiebel K. and Leeb T. 2005 Bovine prion protein gene (PRNP) promoter polymorphisms modulate PRNP expression and may be responsible for differences in bovine spongiform encephalopathy susceptibility. J. Biol. Chem. 280, 37408–37414.

    Article  PubMed  CAS  Google Scholar 

  • Sander P., Hamann H., Pfeiffer I., Wemheuer W., Brenig B., Groschup M. H. et al. 2004 Analysis of sequence variability of the bovine prion protein gene (PRNP) in German cattle breeds. Neurogenetics 5, 19–25.

    Article  PubMed  CAS  Google Scholar 

  • Seabury C. M., Womack J. E., Piedrahita J. and Derr J. N. 2004 Comparative PRNP genotyping of U.S. cattle sires for potential association with BSE. Mamm. Genome 15, 828–833.

    Article  PubMed  CAS  Google Scholar 

  • Walawski K. and Czarnik U. 2003 Prion octapeptide-repeat polymorphism in Polish Black-and-White cattle. J. Appl. Genet. 44, 191–195.

    PubMed  Google Scholar 

  • Westaway D., Cooper C., Turner S., Da Costa M., Carlson G. A. and Prusiner S. B. 1994 Structure and polymorphism of the mouse prion protein gene. Proc. Natl. Acad. Sci. USA 91, 6418–6422.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chaeyoung Lee.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kim, Y., Kim, J.B., Sohn, H. et al. A national survey on the allelic, genotypic, and haplotypic distribution of PRNP insertion and deletion polymorphisms in Korean cattle. J Genet 88, 99–103 (2009). https://doi.org/10.1007/s12041-009-0014-1

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12041-009-0014-1

Keywords

Navigation