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Photochemistry of an alpha lipoic acid-based drug and its application in dual sensing of Fe(III) and Pb(II) and logic gates

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Abstract

The photochemistry of an expired Alpha Lipoic Acid-based drug namely MEGO-XL (ML) was investigated. ML showed its application in selective sensing of Fe3+ and Pb2+ avoiding any interference. The lower detection limit values for Fe3+ (1.51 × 10−4 M) and Pb2+ (72.8 µM) suggested the sensitive nature of ML. The stability of the compound was examined under different environmental conditions. Further, the interaction between ML and Fe3+, Pb2+ was studied with the help of Stern–Volmer plots, Benesi–Hildebrand relation. Increased KSV values with increased temperature suggested that the nature of quenching was purely dynamic in the case of Fe3+ and decreased KSV values with increased temperature indicated that there might be an occurrence of static quenching in the case of Pb2+. Ethylenediaminetetra acetic acid (EDTA) was used to differentiate the detection of Fe3+ from Pb2+.ML also showed application in sensing TiO2 nanoparticles and in OR logic gate operations. These experimental outcomes hinted that the chosen expired drug ML can be reused for chemosensing and logic gate applications.

Graphical abstract

The dual-sensing nature [Fe(III) and Pb(II)] of ML is described through Intensity Vs Wavelength graphs. TiO2 sensing nature of ML is also described by KSV graph. The logic gate application of ML is pictorially represented with a truth table and bar graph.

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Acknowledgements

The authors are thankful to Karnatak University Dharwad for their financial assistance under the scheme of URS (KU/SCH/URS/2018-19/361). The authors thank The Director and Technical staff of USIC, Dharwad for giving the facility of Fluorescence spectrophotometer, UV–Vis spectrometer instruments. We are grateful to DST, New Dehli for providing the FTIR spectrometer instrument facility under the DST-PURSE-phase-II program. [Grant No. SR/PURSE PHASE-2/13(G)]

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  1. Department of Studies in Physics, Karnatak University Dharwad, Dharwad, Karnataka, 580003, India

    Aishwarya Nadgir, Malatesh S Pujar, Shivaprasadagouda Patil & Ashok H Sidarai

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  1. Aishwarya Nadgir
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  2. Malatesh S Pujar
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  3. Shivaprasadagouda Patil
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  4. Ashok H Sidarai
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Correspondence to Ashok H Sidarai.

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Nadgir, A., Pujar, M.S., Patil, S. et al. Photochemistry of an alpha lipoic acid-based drug and its application in dual sensing of Fe(III) and Pb(II) and logic gates. J Chem Sci 134, 8 (2022). https://doi.org/10.1007/s12039-021-02008-y

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  • DOI: https://doi.org/10.1007/s12039-021-02008-y

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