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The worldwide need for amyloid diagnosis in animals

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Abstract

Deposition of amyloid in tissues and organs leads to amyloidosis, impacting the function of vital organs and often resulting in mortality. About 42 proteins in humans and 10 in animals are known to form amyloid deposits. Amyloid research in humans has gained considerable pace in recent years but not in the case of animals. Being an essential part of the ecosystem, animals contribute significantly to the world economy. Many retrospective studies have shown amyloidosis as a possible cause of animal death. Underdiagnosis of amyloidosis in animals may also increase the chance of zoonotic transmission. Hence, assessment of the prevalence of amyloidosis necessitates significant attention. An early diagnosis will improve the overall prognosis and decrease in the fatality of animals. This article strives to bring this issue to the attention of scientists, veterinarians, and primary caretakers of animals. This will help in the diagnosis and treatment of amyloidosis in animals.

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  1. Department of Biological Sciences and Bioengineering, The Mehta Family Centre for Engineering in Medicine, Indian Institute of Technology, Kanpur, 208 016, India

    Akansha Garg & Ashwani Kumar Thakur

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  1. Akansha Garg
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  2. Ashwani Kumar Thakur
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Correspondence to Ashwani Kumar Thakur.

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Corresponding editor: Renee M. Borges

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Garg, A., Thakur, A.K. The worldwide need for amyloid diagnosis in animals. J Biosci 48, 46 (2023). https://doi.org/10.1007/s12038-023-00372-0

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