This is a preview of subscription content, log in via an institution to check access.
References
Eyre-Walker AC 1991 An analysis of codon usage in mammals: selection or mutation bias? J. Mol. Evol. 33 442–449
Kimchi-Sarfaty C, Oh JM, Kim IW, et al. 2007 A ‘silent’ polymorphism in the MDR1 gene changes substrate specificity. Science 315 525–528
Kimura M 1968 Genetic variability maintained in a finite population due to mutational production of neutral and nearly neutral iso-alleles. Genet. Res. 11 247–269
Shen X, Song S, Li C and Zhang J 2022 Synonymous mutations in representative yeast genes are mostly strongly non-neutral. Nature 606 725–731
Tuller T and Zur H 2015 Multiple roles of the coding sequence 5′ end in gene expression regulation. Nucleic Acids Res. 43 13–28
Acknowledgements
The author is grateful to Drs Arun Mahadevan, Savita Chib, Asha M Joseph, Aashiq H Kachroo, Renee M Borges, and Vidyanand Nanjundiah for helpful comments on an earlier version of the manuscript.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Mahadevan, S. Silence of the mutations. J Biosci 47, 74 (2022). https://doi.org/10.1007/s12038-022-00320-4
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s12038-022-00320-4