Abhilash M, Sauganth Paul MV, Varghese MV and Nair RH 2011 Effect of long term intake of aspartame on antioxidant defense status in liver. Food Chem. Toxicol.
Abhilash M, Sauganth Paul MV, Varghese MV and Nair RH 2013 Long-term consumption of aspartame and brain antioxidant defense status. Drug Chem. Toxicol.
Alipour A, van Oostrom AJ, Izraeljan A, Verseyden C, Collins JM, Frayn KN, Plokker TW, Elte JW, et al. 2008 Leukocyte activation by triglyceride-rich lipoproteins. Arterioscler. Thromb. Vasc. Biol.
Alvarez B, Demicheli V, Duran R, Trujillo M, Cervenansky C, Freeman BA and Radi R 2004 Inactivation of human CuZn superoxide dismutase by peroxynitrite and formation of histidinyl radical. Free Rad. Biol. Med.
Auclair C and Voisin E 1985 Nitroblue tetrazolium reduction; in CRC Handbook of methods for oxygen radical research (ed) RA Greenwald (Florida: CRC Press, Boca Raton) pp 123–132
Beutler E 1975 Reduced Glutathione (GSH); in Red cell metabolism, a manual of biochemical methods (ed) E Beutler (New York: Grune and Straton) pp 112–114
Beutler E 1982 Catalase; in Red cell metabolism, a manual of biochemical methods (ed) E Beutler (New York: Grune and Stratton) pp 105–116
Butchko HH, Stargel WW, Comer CP, Mayhew DA, Benninger C, Blackburn GL, de Sonneville LM, Geha RS, et al. 2002 Aspartame: review of safety. Regul. Toxicol. Pharmacol.
Camfield PR, Camfield CS, Dooley JM, Gordon K, Jollymore S and Weaver DF 1992 Aspartame exacerbates EEG spike-wave discharge in children with generalized absence epilepsy: a double blind controlled study. Neurology
Castro GD, Costantini MH, de layno Delgado AM and Castro A 2002 Rat liver microsomal and nuclear activation of methanol to hydroxyl methyl free radicals. Toxicol. Lett.
Chaitanya KV, Pathan AAK, Mazumdar SS, Chakravarthi GP, Parine N and Bobbarala V 2010 Role of oxidative stress in human health: an overview. J. Parm. Res.
Choudhary AK and Devi RS 2014 Imbalance of the oxidant - antioxidant status by aspartame in the organs of immune system of Wistar albino rats. Afr. J. Pharm. Pharmacol.
Dargel R 1991 Lipid peroxidation–a common pathogenic mechanism? Exp. Toxicol. Pathol.
Davoli E, Cappellini L, Airoldi L and Fanelli R 1986 Serum methanol concentration in rats and in men after a single dose of aspartame. Food Chem. Toxicol.
Dejam A, Hunter CJ, Pelletier MM, Hsu LL, Machado RF, Shiva S, Power GG, Kelm M, et al. 2005 Erythrocytes are the major intravascular storage sites of nitrite in human blood. Blood
Djordjević NZ, Babić GM, Marković SD, Ognjanović BI, Stajn AS, Zikić RV and Saičić ZS 2008 Oxidative stress and changes in antioxidative defense system in erythrocytes of preeclampsia in women. Reprod. Toxicol.
Ells JT, Henry MM, Lewandowski MF, Seme MT and Murray T 2000 Development and characterization of a rodent model of methanol-induced retinal and optic nerve toxicity. Neurotoxicol. Rev.
Fernstrom JD, Fernstrom MH and Gillis MA 1983 Acute effects of aspartame on large neutral amino acid and monoamines in rat brain. Life Sci.
Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS and Tannenbaum SR 1982 Analysis of nitrate, nitrite, and [15N] nitrate in biological fluids. Anal. Biochem.
Goerss AL, Wagner GC and Hill WL 2000 Acute effects of aspartame on aggression and neurochemistry in rats. Life Sci.
Halliwell B and Gutteridge JMC 2007 Free radicals in biology and medicine 4th ed. (New York: Oxford University Press) pp 30–110
Hawkins RA, Mans AM and Biebuyck JF 1988 Regional transport and other neutral amino acids across the blood-brain barrier; in Dietary phenylalanine and brain function (eds) RJ Wurtman and E Ritter-Walker (Basel: Birkhauser) pp 63–67
Hayes JD and McLellan LI 1999 Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress. Free Radic. Res.
Herce-Pagliai C, Kotecha S and Shuker D 1998 Analytical methods for 3-nitrotyrosine as a marker of exposure to reactive nitrogen species. A review. Nitric Oxide
Humphries P, Pretorius E and Naude H 2008 Direct and indirect cellular effects of aspartame on the brain. Eur. J. Clin. Nutr.
Iyyaswamy A and Rathinasamy S 2012 Effect of chronic exposure to aspartame on oxidative stress in the brain of albino rats. J. Biosci.
Jang W, Jeoung NH and Cho KH 2011 Modified apolipoprotein (apo) A-I by artificial sweetener causes severe premature cellular senescence and atherosclerosis with impairment of functional and structural properties of apoA-I in lipid-free and lipid-bound state. Mol. Cell.
Kummer U, Zobeley J, Brasen JC, Fahmy R, Kindzelskii AL, Petty AR, Clark AJ and Petty HR 2007 Elevated glucose concentrations promote receptor-independent activation of adherent human neutrophils: an experimental and computational approach. Biophys. J.
Lynch RE and Fridovich I 1978 Permeation of the erythrocyte stroma by superoxide radical. J. Biol. Chem.
Magnuson BA, Burdock GA, Doull J, Kroes RM, Marsh GM, Pariza MW, Spencer PS, Waddell WJ, et al. 2007 Aspartame: a safety elevation based on current use levels, regulations, and toxicological and epidemiological studies. Crit. Rev. Toxicol.
Maher TJ and Wurtman RJ 1987 Possible neurologic effects of aspartame, a widely used food additive. Environ. Health Perspect.
Makhro A, Wang J, Vogel J, Boldyrev AA, Gassmann M, Kaestner L and Bogdanova A 2010 Functional NMDA receptors in rat erythrocytes. Am. J. Physiol. Cell Physiol.
Marklund SL and Marklund G 1974 Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem.
Matés JM 2000 Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology. Toxicology
McMartin KE, Ambre JJ and Tephly TR 1980 Methanol poisoning in human subjects. Role or formic acid accumulation in the metabolic acidosis. Am. J. Med.
McCord JM and Fridovich I 1969 Superoxide dismutase: an enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem.
Moser RH 1994 Aspartame and memory loss. JAMA
Mourad IM 2011 Effect of aspartame on some oxidative stress parameters in liver and kidney of rats. Afr. J. Pharm. Pharmacol.
Mourad IM and Noor NA 2011 Aspartame (a widely used artificial sweetener) and oxidative stress in the rat cerebral cortex. Int. J. Pharm. Biomed. Sci.
Ohkawa H, Okishi N and Yagi K 1979 Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem.
Pacher P, Beckman JS and Liaudet L 2007 Nitric oxide and peroxynitrite in health and disease. Physiol. Rev.
Parthasarathy JN, Ramasundaram SK, Sundaramahalingam M and Pathinasamy SD 2006 Methanol induced oxidative stress in rat lymphoid organs. J. Occup. Health
Petnehazy T, Stokes KY, Wood KC, Russell J and Granger DN 2006 Role of blood cell-associated AT1 receptors in the microvascular responses to hypercholesterolemia. Arterioscler. Thromb. Vasc. Biol.
Pick E and Keisari Y 1980 A simple colorimetric method for the measurement of hydrogen peroxide produced by cells in culture. J. Immunol. Methods
Riordan JF and Vallee BL 1972 Nitration with tetranitromethane; in Methods in Enzymology (eds) CHW Hirs and SN Timasheff (New York: Academic Press) 25 515–521
Stegink LD 1987 The aspartame story: a model for the clinical testing of a food additive. Am. J. Clin. Nutr.
Sugano R, Matsuoka H, Haramaki N, Umei H, Murase E, Fukami K, Iida S, Ikeda H, et al. 2005 Polymorphonuclear leukocytes may impair endothelial function: results of crossover randomized study of lipid-lowering therapies. Arterioscler. Thromb. Vasc. Biol.
Tephly TR 1991 The toxicity of methanol. Life Sci.
Van den Eeden SK, Koepsell TD, Longstreth WT Jr, van Belle G, Daling JR and McKnight B 1994 Aspartame ingestion and headaches: a randomized crossover trial. Neurology
Walton RG 1988 The possible role of aspartame in seizure induction; in Dietary phenylalanine and brain function (eds) RJ Wurthman and E Ritter-Walker (Boston: Birkhauser) pp 159–162
Wang X, Tanus-Santos JE, Reiter CD, Dejam A, Shiva S, Smith RD, Hogg N and Gladwin MT 2004 Biological activity of nitric oxide in the plasmatic compartment. Proc. Natl. Acad. Sci. U. S. A.
Wink DA and Mitchell JB 1998 Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide. Free Radic. Biol. Med.
Winterbourn CC and Stern A 1987 Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxycal radical. J. Clin. Invest.