Abstract
COVID-19 inflicted by the SARS-CoV-2 virus has created mayhem across the globe and has afflicted socio-economic, political and cultural aspects of every nook of the world. Notwithstanding, the ensuing COVID-19 waves are still approaching and squeezing the economies of developed and developing worlds. Nanobiotechnology-driven interventions in COVID-19 may facilitate nipping in the bud at an early stage, consequently managing the menace of the virus. Nanostructures, notably luminescent carbon/quantum dots (C/QD), are potential nanomedicines in the field of theranostics and pharmaceuticals. They have stood the test of time due to their ease of synthesis, minimal toxicity, significant biocompatibility, tunable fluorescence, surface tenability, excellent photochemical stability and good hydrophilicity. In this mini-review, we have considered the recent findings of C/QD as potential nano-theranostics against COVID-19. Furthermore, we have also discussed antiviral modes of different C/QD. This mini-review will provide brief oversight and offer a new strategy to develop C/QD-based antiviral agents for future-ready pandemics.
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Acknowledgements
ANS is thankful to the Department of Biotechnology, Ministry of S & T, Government of India, New Delhi, India, for providing the funding (DBT’s sanction order No. BT/PR25498/NER/95/1223/2017) for exploring phytochemical and pharmacological evaluation of bioactivity guided fractions of medicinal plants. We thank the Ministry of Education, New Delhi, and the Department of Pharmaceutical Engineering & Technology at the IIT (BHU) for their support. ANS is also thankful to Uttar Pradesh Council of Science and Technology Project ID 752 for providing funding for developing carbon Nanodots for oral cancer.
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Naik, G.G., Mohapatra, D., Shreya, S. et al. Nip in the bud: can carbon/quantum dots be a prospective nano-theranostics against COVID-19?. Bull Mater Sci 47, 6 (2024). https://doi.org/10.1007/s12034-023-03084-1
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DOI: https://doi.org/10.1007/s12034-023-03084-1