Molecular Biotechnology

, Volume 37, Issue 1, pp 26–30 | Cite as

Carotenoids and Flavonoids Contribute to Nutritional Protection against Skin Damage from Sunlight

  • Wilhelm Stahl
  • Helmut Sies


The concept of photoprotection by dietary means is gaining momentum. Plant constituents such as carotenoids and flavonoids are involved in protection against excess light in plants and contribute to the prevention of UV damage in humans. As micronutrients, they are ingested with the diet and are distributed into light-exposed tissues, such as skin or the eye where they provide systemic photoprotection. β-Carotene and lycopene prevent UV-induced erythema formation. Likewise, dietary flavanols exhibit photoprotection. After about 10–12 weeks of dietary intervention, a decrease in the sensitivity toward UV-induced erythema was observed in volunteers. Dietary micronutrients may contribute to life-long protection against harmful UV radiation.


Photoprotection Micronutrients Carotenoids Flavonoids Erythema 



The lycopene project was supported in part by the Bundesministerium für Bildung und Forschung, Bonn (Project: 0312248C). The flavanol project was supported by Mars Inc. (Hackettstown, NJ) and by Krebsforschung International e.V. (Düsseldorf, Germany). H.S. is a Fellow of the National Foundation for Cancer Research (NFCR), Bethesda, MD.


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Copyright information

© Humana Press Inc. 2007

Authors and Affiliations

  1. 1.Institut für Biochemie und Molekularbiologie I, Heinrich-Heine-Universität DüsseldorfDusseldorfGermany

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