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On the role of polyploid giant cells in oncogenesis and tumorigenesis

  • Letter to the Editor
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A Letter to the Editor to this article was published on 02 September 2023

The Original Article was published on 01 May 2023

A Short Communication to this article was published on 09 March 2023

Abstract

This correspondence is in response to the commentary by Jinsong Liu (https://doi.org/10.1007/s12032-023-02038-1) to my article “The evolutionary cancer gene network theory versus embryogenic hypotheses” published in Medical Oncology (40:114, 2023). Liu’s commentary engages head-on with the evolutionary cancer genome theory and defends his more histopathologically-embryogenically oriented theory of 2020. The dispute revolves, among other things, around the role of polyploid giant MGRS/PGCCs structures in oncogenesis and tumorigenesis.

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References

  1. Niculescu VF. The evolutionary cancer genome theory and its reasoning. Genet Med Open. 2023;1:100809.

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  2. Niculescu VF. Dysregulated cells that lose stemness and ACD function increase cancer risk. Genes Dis 2023.

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Authors and Affiliations

  1. Diedorf, Augsburg, Bavaria, Germany

    Vladimir F. Niculescu

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  1. Vladimir F. Niculescu
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Correspondence to Vladimir F. Niculescu.

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Niculescu, V.F. On the role of polyploid giant cells in oncogenesis and tumorigenesis. Med Oncol 40, 232 (2023). https://doi.org/10.1007/s12032-023-02089-4

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  • DOI: https://doi.org/10.1007/s12032-023-02089-4

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