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Uterine fibroid therapy using interventional radiology mini-invasive treatments: current perspective

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Abstract

Uterine fibroids are common benign tumors of unclear etiopathology that affect the female reproductive tract. They are responsible for considerable morbidity and deterioration of life quality, and may have a negative impact on the reproductive system as well. Besides surgery aided by uterus-saving techniques, several minimally invasive procedures are now available within the field of interventional radiology that represent a valid solution for women who desire pregnancy and relief from disease-specific symptomatology. The main advantages offered by these techniques are low grade of invasiveness and short times of hospitalization. The most diffuse techniques are uterine artery embolization (UAE) and magnetic resonance-guided high-intensity focused ultrasound (MRgFUS). UAE is an endovascular procedure whose goal is obtained by provoking ischemia of the uterine vessels. MRgFUS is a thermoablation procedure that selectively ablates the symptomatic fibroids. In this review study, both procedures will be described, including a description of technical details, indications, contraindications, complications, and outcomes.

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Acknowledgements

The Authors wish to thank Angela Martella for translation of the manuscript.

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Authors and Affiliations

  1. Diagnostic and Interventional Radiology, Department of Applied Clinical Science and Biotechnology, University of L’Aquila, L’Aquila, Italy

    Carlo Masciocchi, Francesco Arrigoni, Fabiana Ferrari, Aldo Victor Giordano, Sonia Iafrate, Ilaria Capretti, Ester Cannizzaro & Antonio Barile

  2. Department of Internal and Experimental Medicine, Magrassi-Lanzara, Institute of Radiology, Second University of Naples, Naples, Italy

    Alfonso Reginelli

  3. Department of Radiology, Insubria University, Varese, Italy

    Anna Maria Ierardi & Chiara Floridi

  4. Diagnostic and Interventional Radiology Unit, University of Milan, Milan, Italy

    Alessio Salvatore Angileri

  5. Department of Medicine and Health Science “V. Tiberio”, University of Molise, Campobasso, Italy

    Luca Brunese

Authors
  1. Carlo Masciocchi
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  2. Francesco Arrigoni
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  3. Fabiana Ferrari
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  5. Sonia Iafrate
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  6. Ilaria Capretti
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  7. Ester Cannizzaro
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  8. Alfonso Reginelli
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  9. Anna Maria Ierardi
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  10. Chiara Floridi
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  11. Alessio Salvatore Angileri
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  12. Luca Brunese
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  13. Antonio Barile
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Corresponding author

Correspondence to Carlo Masciocchi.

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Informed consent

All procedures performed in this study were in accordance with the Helsinki Declaration and its later amendments; an informed consent was obtained from all individual participants included in the study.

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Masciocchi, C., Arrigoni, F., Ferrari, F. et al. Uterine fibroid therapy using interventional radiology mini-invasive treatments: current perspective. Med Oncol 34, 52 (2017). https://doi.org/10.1007/s12032-017-0906-5

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  • DOI: https://doi.org/10.1007/s12032-017-0906-5

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