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Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance

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References

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The authors declare no conflict of interest.

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Authors and Affiliations

  1. Laboratory of Computational Biochemistry, KN Biomedical Research Institute, Bagura Road, Barisal, Bangladesh

    Nuzhat N. Kabir & Julhash U. Kazi

  2. Experimental Clinical Chemistry, Department of Laboratory Medicine, Lund University, Wallenberg Laboratory, Skåne University Hospital, 20502, Malmö, Sweden

    Julhash U. Kazi

Authors
  1. Nuzhat N. Kabir
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  2. Julhash U. Kazi
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Correspondence to Julhash U. Kazi.

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Kabir, N.N., Kazi, J.U. Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance. Med Oncol 30, 448 (2013). https://doi.org/10.1007/s12032-012-0448-9

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  • DOI: https://doi.org/10.1007/s12032-012-0448-9

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