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Frequency of HCV infection in renal cell carcinoma patients

Medical Oncology volume 29, pages 1892–1895 (2012)Cite this article

Abstract

Chronic infections with hepatitis C virus (HCV) are frequently pronounced in the etiology of malignancies especially in hepatocellular carcinoma. The association between HCV and risk of renal cell carcinoma (RCC) development has been stated recently. The authors retrospectively evaluated hepatitis serology for HCV and HBV in patients who had RCC diagnosis between 2005 and 2010 in six oncology centers. Control group was also included from the three different published studies that hepatitis serology studied in healthy people that has been living in the same geographic regions. Histologically confirmed 903 RCC cases and 5,267 healthy subjects were included the study. Median age at diagnosis of RCC was 58 (range: 26–89). There was no increase in HCV positivity in RCC patients compared to healthy control group (1.7 vs. 1.5%; P = 0.77). Frequency of HBsAg positivity was 4.4 and 4.1% in RCC and control groups, respectively (P = 0.65). There is no increase in frequency of HCV and HBsAg positivity in RCC patients. HCV positivity in RCC patients were not different from the healthy people.

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Affiliations

  1. Department of Medical Oncology, Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital, Ankara, Turkey

    Burçin Budakoğlu, Ümmügül Üyetürk, İbrahim Türker & Berna Öksüzoğlu

  2. Department of Medical Oncology, Ankara Numune Education and Research Hospital, 06100, Sihhiye, Ankara, Turkey

    Sercan Aksoy, Nalan Akgül Babacan, Nuriye Yıldırım Özdemir, M. Bülent Akıncı & Nurullah Zengin

  3. Department of Medical Oncology, Hacettepe University Institute of Oncology, Ankara, Turkey

    Çağatay Arslan & Kadri Altundag

  4. Department of Urology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey

    Muhammet Fuat Özcan

  5. Department of Medical Oncology, Dr. Lutfi Kirdar Education and Research Hospital, Istanbul, Turkey

    Ramazan Yıldız & Başak Bala Öven

  6. Department of Medical Oncology, Ankara Atatürk Education and Research Hospital, Ankara, Turkey

    Ömer Dizdar

  7. Department of Medical Oncology, Gazi University Faculty of Medicine, Ankara, Turkey

    Süleyman Büyükberber

Authors
  1. Burçin Budakoğlu
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  2. Sercan Aksoy
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  3. Çağatay Arslan
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  4. Ümmügül Üyetürk
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  5. Nalan Akgül Babacan
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  6. Muhammet Fuat Özcan
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  7. Ramazan Yıldız
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  8. Başak Bala Öven
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  9. Nuriye Yıldırım Özdemir
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  10. Ömer Dizdar
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  11. Süleyman Büyükberber
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  12. M. Bülent Akıncı
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  13. İbrahim Türker
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  14. Berna Öksüzoğlu
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  15. Kadri Altundag
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  16. Nurullah Zengin
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Corresponding author

Correspondence to Sercan Aksoy.

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Budakoğlu, B., Aksoy, S., Arslan, Ç. et al. Frequency of HCV infection in renal cell carcinoma patients. Med Oncol 29, 1892–1895 (2012). https://doi.org/10.1007/s12032-011-9928-6

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  • DOI: https://doi.org/10.1007/s12032-011-9928-6

Keywords

  • Hepatitis C virus
  • Renal cell carcinoma
  • HBsAg