Medical Oncology

, Volume 28, Issue 4, pp 948–950 | Cite as

Spontaneous complete regression of hepatocellular carcinoma

  • Raul E. StoreyEmail author
  • Ana L. Huerta
  • Amir Khan
  • Damian A. Laber
Original Paper


In medical terminology, spontaneous regression of cancer refers to exceptional and unexplained partial or complete disappearance of cancer without medical intervention. This phenomenon has been described in various malignancies with no well established causative factors, except perhaps immune mediated. Here we present a rare case of hepatocellular carcinoma with possible metastasis to the lung by computed tomography with complete regression of both the primary tumor and the pulmonary nodules without medical intervention. Our patient may represent the first case of complete regression of the HCC with possible lung metastasis by computed tomography caused by abstinence from alcohol. This phenomenon was confirmed by surgical resection and pathologic evaluation.


Spontaneous regression Hepatocellular carcinoma Liver cancer 



This study was not funded by any source and the authors have nothing to disclose.


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Raul E. Storey
    • 2
    Email author
  • Ana L. Huerta
    • 1
  • Amir Khan
    • 1
  • Damian A. Laber
    • 2
  1. 1.Internal Medicine Department, Paul L. Foster School of MedicineTexas Tech University Health Sciences CenterEl PasoUSA
  2. 2.Department of Medicine, Division of Hematology-Oncology, James G. Brown Cancer CenterUniversity of LouisvilleLouisvilleUSA

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