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Colorectal Cancer Prevalence and Survival in Cuenca (Spain)

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Abstract

Background

Colorectal cancer is the most commonly diagnosed cancer type and the second cause of cancer death in Spain. The primary risk factor for colorectal cancer is age, with 90% of all diagnosed patients aged over 50 years. Prognosis mainly depends on tumour stage.

Aim

Conduct a colorectal cancer prevalence and survival study in Cuenca (Spain) since there are almost no studies based on small populations. This is the first study about survival in screening of colorectal cancer carried out in hospitals in Castilla-La Mancha.

Methods

Retrospective descriptive cohort study was performed to include patients with colorectal cancer diagnosed by colonoscopy between May 2015 and April 2016, and who were followed up for 48 months. The study considered sociodemographic and clinical data of the patients. Survival curves were estimated using the Kaplan–Meier method. The proportional hazard rate associated with age, gender, stage, and presence of metastasis was calculated using the Cox regression method.

Results

Fifty-seven patients were included in the study. The mean follow-up was 45.5 months. Ten patients died during the study; in seven cases, the cause was colorectal cancer. The percentage of patients alive at a 48-month follow-up was 82.4%.

Conclusion

Colon cancer is a high-prevalence pathology, with adenocarcinoma being the most common histology. The results seem to indicate that it affects men more frequently, mortality rises with tumour stage at diagnosis and declines with use of chemotherapy. We present a study that could justify large-scale epidemiological studies for the regional surveillance and evolution of colorectal cancer in Spain.

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Data Availability

The authors confirm that the data supporting the findings of this study are available within the article and its supplementary materials.

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Funding

The present study received no funding from the public, private or non-profit sectors. Francisco Escribano Sotos was funded by the University of Castilla-La Mancha “Support for Research Groups 2019- Economy, Food and Society Group”.

Author information

Authors and Affiliations

  1. Department of Gastroenterology, Virgen de La Luz Hospital, Cuenca, Spain

    Laura Valiente González

  2. Department of General and Digestive Surgery, Virgen de La Luz Hospital, Cuenca, Spain

    Ricardo de Miguel Ibáñez

  3. Faculty of Economics and Business Administration, University of Castilla-La Mancha, Albacete, Spain

    Francisco Escribano Sotos

Authors
  1. Laura Valiente González
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  2. Ricardo de Miguel Ibáñez
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  3. Francisco Escribano Sotos
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Corresponding author

Correspondence to Laura Valiente González.

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Ethics Approval

This study was approved by the Ethics Committee for Clinical Research of the Health Services Area of Cuenca (REG: 2019/PI1919) in December 2019.

Conflict of Interest

The authors declare no competing interests.

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González, L.V., de Miguel Ibáñez, R. & Sotos, F.E. Colorectal Cancer Prevalence and Survival in Cuenca (Spain). J Gastrointest Canc 54, 80–89 (2023). https://doi.org/10.1007/s12029-021-00784-x

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