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Laparoscopic Partial Gastrectomy for Large Gastric GISTs

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Abstract

Background

Gastrointestinal stromal tumors (GISTs) are considered the most common mesenchymal tumors in the gastrointestinal tract and the stomach is the most frequently site affected (50–60%). The safety and feasibility of laparoscopic surgery for gastric GISTs of sizes larger than 5 cm remains unclear. It depends on the surgical skills, tumor location, and the learning curve of the surgeons.

Methods

Between December 2013 and January 2021, 30 patients diagnosed with gastric GISTs underwent laparoscopic partial gastrectomy. This is a retrospective study done in Surgical Oncology unit, Oncology Center, Mansoura University, Egypt.

Results

The most common tumor location was in the greater curvature in (46.7%). The mean tumor size was 9.5 cm (range 5–17 cm). All of the patients underwent laparoscopic partial gastrectomy. Associated splenectomy was done for only one patient. The mean operative time was 152.67 min and the estimated blood loss (EBL) was 139.33 ml. The mean hospital stay was 3.53 days. The mean follow-up period was 32.4 months.

Conclusion

Laparoscopic resection for gastric GISTs has become a feasible method. Patients with large tumors have the same favorable outcomes as small tumors. Large-sized GISTs may receive neoadjuvant therapy to downstage the disease and make it amenable for laparoscopic resection.

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Authors and Affiliations

  1. Department of Surgery, Surgical Oncology Unit, Oncology Center Mansoura University (OCMU), Gomhouria St., Mansoura, 35516, Egypt

    Amr Abouzid, Ahmed Setit, Adel Fathi & Mosab Shetiwy

Authors
  1. Amr Abouzid
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  2. Ahmed Setit
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  3. Adel Fathi
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  4. Mosab Shetiwy
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Contributions

All authors have made substantial contributions to conceptualization, methodology, validation, formal analysis, investigation, writing original draft, review and editing, visualization, and project administration. All authors have approved the submitted version of the article.

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Correspondence to Amr Abouzid.

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Ethics Approval

Approval is from the Institutional Review Board (IRB) of Faculty of Medicine, Mansoura University code (R.21.03.1266).

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The authors declare no competing interests.

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Abouzid, A., Setit, A., Fathi, A. et al. Laparoscopic Partial Gastrectomy for Large Gastric GISTs. J Gastrointest Canc 53, 564–570 (2022). https://doi.org/10.1007/s12029-021-00658-2

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  • DOI: https://doi.org/10.1007/s12029-021-00658-2

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