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Outcomes of Partial or Total Cystectomy in Advanced Colon Cancer with Suspected Bladder Invasion—Our 8-Year Experience and Literature Review

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Abstract

Purpose

Advanced colon cancers with bladder invasion pose a heavy burden and challenge towards patients and surgeons. Herein, we report our series with regards to operative and oncological outcomes in our 8 years of experience.

Methods

All patients with advanced colonic tumours and suspected bladder invasion being operated from 2012 to 2020 were included. The histological findings, clinical and oncological outcomes were evaluated.

Results

Twenty-two patients were included. Partial cystectomy was performed in 17 of them (77%). No neoadjuvant treatment was prescribed. All preoperative computed tomography (CT) scan showed bladder invasion or colovesical fistula. True tumour invasion to bladder (T4b disease) was confirmed in 17 patients (77%) by histopathology. The 3-year overall survival and recurrence rates were 82% and 9%, respectively.

Conclusion

En bloc resection of colonic tumour with adherent bladder in advanced colon cancers can achieve a good operative and oncological outcome without neoadjuvant therapy. The relatively low concordance rate between preoperative CT scan and final histopathology may limit the benefit of routine administration of neoadjuvant therapy as it may overtreat and delay subsequent oncological treatment of our patients with possible added morbidity.

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Authors and Affiliations

  1. Department of Surgery, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China

    Tsang Yi Po & Lau Chi Wai

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  1. Tsang Yi Po
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  2. Lau Chi Wai
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Correspondence to Tsang Yi Po.

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Tsang, Y., Lau, C. Outcomes of Partial or Total Cystectomy in Advanced Colon Cancer with Suspected Bladder Invasion—Our 8-Year Experience and Literature Review. J Gastrointest Canc 53, 394–402 (2022). https://doi.org/10.1007/s12029-021-00623-z

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