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Low-grade Mucinous Appendiceal Neoplasm: a Tumor in Disguise of Appendicitis

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Abstract

Appendiceal mucinous neoplasms are a rare malignancy, but it is an important diagnostic entity. Ultrasonography and CT scan represent useful method for diagnosis; however, diagnosis is often incidental or intraoperative finding at resection for suspicion of appendicitis. Appendiceal mucinous neoplasm is commonly misdiagnosed as acute appendicitis, adnexal mass, or retroperitoneal tumors. Our case represents the importance of developing a high index of suspicion of appendiceal malignancy and mucocele rupture in patients who are planned for appendectomy. There is risk of second malignancy mostly of ovary, breast, kidney, and gastrointestinal tract simultaneously in about 30% of patients of appendiceal mucinous neoplasm. Low-grade mucinous neoplasm has excellent prognosis after standard appendectomy. Advanced stage low-grade mucinous neoplasm involving periappendiceal area or with nodal metastasis is treated by appendectomy with right hemicolectomy and lymph node dissection. We report a case of low-grade appendiceal mucinous neoplasm in a 65-year-old female with past history of surgery for benign bilateral adnexal lesions.

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Authors and Affiliations

  1. Department of Radiation Oncology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Rajasthan, India

    Tej Prakash Soni

  2. Department of Surgical Oncology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Rajasthan, India

    Prashant Sharma & Naresh Ledwani

  3. Department of Pathology, Bhagwan Mahaveer Cancer Hospital and Research Centre, Jaipur, Rajasthan, India

    Anjali Sharma

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  1. Tej Prakash Soni
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  2. Prashant Sharma
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  3. Anjali Sharma
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  4. Naresh Ledwani
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Contributions

Tej Prakash Soni: conception and design of this study, acquisition of data, analysis and interpretation of data, revising the manuscript critically for important intellectual content, drafting, and approval of the manuscript; Prashant Sharma: analysis and interpretation of data, revising the manuscript critically for important intellectual content, and approval of the manuscript; Anjali Sharma: analysis and interpretation of data, revising the manuscript critically for important intellectual content, and approval of the manuscript; Naresh Ledwani: analysis and interpretation of data, revising the manuscript critically for important intellectual content, and approval of the manuscript

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Correspondence to Tej Prakash Soni.

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Soni, T.P., Sharma, P., Sharma, A. et al. Low-grade Mucinous Appendiceal Neoplasm: a Tumor in Disguise of Appendicitis. J Gastrointest Canc 52, 1134–1138 (2021). https://doi.org/10.1007/s12029-021-00593-2

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  • DOI: https://doi.org/10.1007/s12029-021-00593-2

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