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Disaggregating Data on Pacific Islander Gastric Cancer Patients Reveals Survival Disparity

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Abstract

Purpose

The incidence and prognosis of Pacific Islanders with gastric cancer is not well documented as previous studies have often aggregated this population with Asians. The purpose of our study was to describe patient and tumor characteristics, as well as prognostic factors of Pacific Islanders with gastric cancer.

Methods

Patients diagnosed with gastroesophageal junction or gastric adenocarcinoma between 2000 and 2014 were identified in the tumor registry of the largest hospital in Hawaii. Overall survival of Asians, Whites, and Pacific Islanders were calculated using the Kaplan-Meier method and log-rank test. Cox proportional hazards regression models were constructed to assess predictors of survival adjusting for clinical and pathological factors.

Results

A total of 615 patients were included in the final analysis. Pacific Islanders were found to present at a younger age, were more often uninsured or had Medicaid insurance, and were diagnosed with a higher stage of cancer compared to their Asian and White counterparts. Pacific Islanders were less likely to undergo surgery even after adjusting for stage. Race was a prognostic factor and survival was lowest among Pacific Islanders, but only if the model was unadjusted for treatment.

Conclusions

We present an analysis of the largest cohort of Pacific Islander gastric cancer patients. Pacific Islanders have different sociodemographic characteristics and inferior survival compared to Asian patients and should be independently studied.

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Data Availability

Raw data was obtained from the Queen’s Medical Center (QMC), Honolulu, Hawaii, Oncology Data Registry (ODR), and the QMC Pathology Department. Derived data supporting the findings of this study are available from the corresponding author on request.

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Authors and Affiliations

  1. University of Hawai’i Internal Medicine Residency Program, Honolulu, HI, USA

    Gene T. Yoshikawa

  2. John A. Burns School of Medicine, University of Hawai’i at Manoa, Honolulu, HI, USA

    Nicholas Simon

  3. Internal Medicine Department, University of Hawai’i, Honolulu, HI, USA

    Ryon K. Nakasone & Jared D. Acoba

  4. University of Hawai’i Cancer Center, Honolulu, HI, USA

    Jared D. Acoba

  5. Queen’s Medical Center, Honolulu, HI, USA

    Jared D. Acoba

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  1. Gene T. Yoshikawa
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  2. Nicholas Simon
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  4. Jared D. Acoba
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Correspondence to Jared D. Acoba.

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Yoshikawa, G.T., Simon, N., Nakasone, R.K. et al. Disaggregating Data on Pacific Islander Gastric Cancer Patients Reveals Survival Disparity. J Gastrointest Canc 53, 144–150 (2022). https://doi.org/10.1007/s12029-020-00579-6

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  • DOI: https://doi.org/10.1007/s12029-020-00579-6

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