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Extricating the Association Between the Prognostic Factors of Colorectal Cancer



Colorectal cancer (CRC) is one of the recurring and lethal gastrointestinal tract disease rankings as the primary cause of worldwide morbidity and mortality. In general, the tumour node metastasis (TNM) and Dukes classification assist in diagnosis, prognosis and treatments of CRC along with haematological examinations and tumour demographic characterisations in patients.


The present investigation is carried out on clinically acknowledged sixty-five CRC patients based on haematological findings and are sorted into stages using TNM and Dukes. The present study is to find the association between haematological findings, demographic characters, differentiation position, lymph node invasion and tumour node metastasis in CRC patients in accordance with their age.


We observed significant (p < 0.05) nexus between lymph node metastasis and tumour node metastasis on the basis of tumour’s differentiation demographic positioning and age of the individuals.


Earlier location tracing and medicinal treatment or surgery lessen the chance of CRC morbidity and mortality along with prolonging survival rate via prognostic factors and disease position determination.

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The authors thank the Management of Bharathiar University for providing infrastructure facilities for this research work and the subjects who volunteered to take part in this study from hospitals in and around Coimbatore, Tamil Nadu, India.


Mohd Younis acknowledge the financial support from the council of DST-PURSE, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, Tamil Nadu, India.

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Authors and Affiliations



V.A., B.B. and S.K conceived and designed the study; M.Y., A.M., B.B., K.A., S.S., M.K.R. and V.A. examined and supervised the clinical and experimental data interpretation; M.V.A., M.P., B.B. and V.A. critically revised and edited the manuscript; M.Y., A.M., K.A., H.K.B and S.S. data curation, analysed the data and drafted the manuscript; M.Y., A.M. and M.V.A., performed the statistical and writing—original draft preparation; All authors read and critically revised the manuscript and approved the final version.

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Correspondence to Vijaya Anand Arumugam.

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Balamuralikrishnan Balasubramanian and Arun Meyyazhagan are equal contributors and are first authors.

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Mohd, Y., Balasubramanian, B., Meyyazhagan, A. et al. Extricating the Association Between the Prognostic Factors of Colorectal Cancer. J Gastrointest Canc 52, 1022–1028 (2021).

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  • Colorectal cancer
  • Haematology
  • Lymph node metastasis
  • Staging