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All data generated or analyzed during this study are included in this published article.
Abbreviations
- AML:
-
Acute Myeloid Leukemia
- CD:
-
Cluster of differentiation
- CT:
-
Computed tomography
- DNA:
-
Deoxyribonucleic acid
- DOG-1:
-
Discovered on gastrointestinal stromal tumors GIST-1
- EMA:
-
Epithelial membrane antigen
- GIST:
-
Gastrointestinal stromal tumor
- ITK`:
-
Inhibitors of the tyrosine kinase
- KIT:
-
Tyrosine-protein kinase C-kit
- MRI:
-
Magnetic resonance imaging
- PDGFRA:
-
Platelet-derived growth factor receptor
- SMA:
-
Smooth muscle antigen
References
Ducimetiere F, Lurkin A, Ranchere-Vince D, et al. Incidence of sarcoma histotypes and molecular subtypes in a prospective epidemiological study with central pathology review and molecular testing. PLoS One. 2011;6(8):e20294.
Miettinen M, Majidi M, Lasota J. Pathology and diagnostic criteria of gastrointestinal stromal tumors (GISTs): a review. Eur J Cancer. 2002;38(5):39–51.
Joensuu H, DeMatteo RP. The management of gastrointestinal stromal tumors: a model for targeted and multidisciplinary therapy of malignancy. Annu Rev Med. 2012;63:247–58.
Aderemi O, Samuel K, Abimbola J, Philip O. Gastrointestinal stromal tumor of the anal wall in a Nigerian. Pan Afr Med J. 2015;22:161.
Fletcher CDM, Berman JJ, Corless C, Gorstein F, Lasota J, Longley JB, et al. Diagnosis of gastrointestinal stromal tumors: a consensus approach. Hum Pathol. 2002;33(5):459–65.
Tworek JA, Goldblum JR, Weiss SW, Greenson JK, Appelman HD. Stromal tumors of the anorectum: a clinicopathologic study of 22 cases. Am J Surg Pathol. 1999;23:946–54.
Miettinen M, Furlong M, Sarlomo-Rikala M, Burke A, Sobin LH, Lasota J. Gastrointestinal stromal tumors, intramural leiomyomas, and leiomyosarcomas in the rectum and anus: a clinicopathologic, immunohistochemical, and molecular genetic study of 144 cases. Am J Surg Pathol. 2001;25:1121–33.
Scow JS, Mathis KL. Gastrointestinal stromal tumors (GIST) of the anus: a single institution experience. Turk J Gastroenterol. 2019;30(6):576–7.
Changchien CR, Wu MC, Tasi WS, Tang R, Chiang JM, Chen JS, et al. Evaluation of prognosis for malignant rectal gastrointestinal stromal tumor by clinical parameters and immunohistochemical staining. Dis Colon Rectum. 2004;47(11):1922–9.
Kashu N, Yasuda K, Yoshitake H, Takami T, Kataoka N, Yamaguchi T, et al. A case of gastrointestinal stromal tumor in the rectum with preservation of anal function after neoadjuvant chemotherapy usingImatinib. Gan To Kagaku Ryoho. 2019;46(13):2383–5.
Carvalho N, Albergaria D, Lebre R, Giria J, Fernandes V, Vidal H, et al. Anal canal gastrointestinal stromal tumors: case report and literature review. World J Gastroenterol. 2014 Jan 7;20(1):319–22.
Li JC, Ng SS, Lo AW, Lee JF, Yiu RY, Leung KL. Outcome of radical excision of anorectal gastrointestinal stromal tumors in Hong Kong Chinese patients. Indian J Gastroenterol. 2007;26(1):33–5.
Singhal S, Singhal A, Tugnait R, Varghese V, Tiwari B, Arora PK, et al. Anorectal gastrointestinal stromal tumor: a case report and literature review. Case Rep Gastrointest Med. 2013;2013:934875.
Cohen NA, Kim TS, DeMatteo RP. Principles of kinase inhibitor therapy for solid tumors. Ann Surg. 2017;265(2):311–9.
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TD is responsible for the conception of the study, participated in the study design, performed the laboratory analysis and interpretation, and wrote the paper. MT, BT, TDj, AB, and FA were involved in the clinical and therapeutic management of the patient; they have reviewed the paper. GNK was responsible for the overall scientific management of the study and the preparation of the final paper. All the authors have read and approved the final paper to be submitted for publication.
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This case report was approved by the Department of Pathology of CHU of Lomé, University of Lomé. This study was approved by the head of the laboratory department of the Sylvanus Olympio University Hospital (Ref N° 007/2020/LAP/CHUSO/UL).
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Written informed consent for publication of their clinical details and clinical images was obtained from the patient. A copy of the consent form is available for review by the Editor of this journal.
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Darré, T., Tchaou, M., Tchangaï, B. et al. Anal Canal Gastrointestinal Stromal Tumor: a Case Report. J Gastrointest Canc 52, 306–309 (2021). https://doi.org/10.1007/s12029-020-00415-x
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DOI: https://doi.org/10.1007/s12029-020-00415-x