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Trends in Mortality Rates for Gastrointestinal Cancers in Fars Province, Iran (2005–2015)

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Abstract

Purpose

In Iran, cancers are the third leading cause of death, and gastrointestinal cancers are the primary cause of mortality among all the cancers. This study aimed to determine the trend of crude and age-standardized mortality rates (ASMR) for different types of gastrointestinal cancers over an 11-year period in Fars province (Iran).

Methods

In this study, all the mortality data for gastrointestinal cancers were derived from the Electronic Death Registration System (EDRS) between 2005 and 2015. Subsequently, we calculated the crude and age-standardized mortality rates (ASMR) and their trends for different types of gastrointestinal cancers based on age groups and gender over the study period.

Results

A total of 6547 deaths from gastrointestinal cancers were identified, with an average age of 66.0 ± 16.4 years. The crude and age-standardized mortality rates for gastrointestinal cancers were respectively 10.9 and 15.0 per 100,000 population in 2005 which significantly increased to 17.4 and 19.4 per 100,000 population in 2015 (P < 0.001). The ASMR for colon, pancreatic, and oral cancers showed an increasing trend; for small intestine cancers, a decreasing trend; and for esophageal, gastric, rectal, and hepatobiliary cancers displayed an almost constant trend.

Conclusions

Our study shows a higher ASMR and an increasing trend of gastrointestinal cancers in Fars province. Prevention and early diagnosis programs with screening techniques should be implemented to control the mortality rate of gastrointestinal cancers in the future.

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Funding

This study was financially approved by Shiraz University of Medical Sciences, Shiraz, Iran (Grant number 96-01-109-14806).

Author information

Authors and Affiliations

  1. Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran

    Hossein-Ali Nikbakht

  2. Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran

    Hossein-Ali Nikbakht

  3. Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD, USA

    Sadaf Sahraian

  4. Research Center for Health Sciences, Institute of Health, Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran

    Haleh Ghaem

  5. Statistics Department, Health Vice-chancellor, Shiraz University of Medical Sciences, Shiraz, Iran

    Afshan Javadi

  6. Medical Records, Health Vice-chancellor, Shiraz University of medical sciences, Shiraz, Iran

    Maryam Janfada

  7. Gastrointestinal & Liver Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran

    Soheil Hassanipour

  8. Non-communicable Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Ali-Reza Mirahmadizadeh

  9. Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran

    Ali-Reza Mirahmadizadeh

Authors
  1. Hossein-Ali Nikbakht
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  2. Sadaf Sahraian
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  7. Ali-Reza Mirahmadizadeh
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Corresponding author

Correspondence to Ali-Reza Mirahmadizadeh.

Ethics declarations

This study was conducted in compliance with the provisions of the Helsinki Declaration. The protocol was approved by the ethics committee of Shiraz University of Medical Sciences (No. IR.SUMS.REC. 1396.S619).

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The authors declare that they have no conflict of interest.

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Nikbakht, HA., Sahraian, S., Ghaem, H. et al. Trends in Mortality Rates for Gastrointestinal Cancers in Fars Province, Iran (2005–2015). J Gastrointest Canc 51, 63–69 (2020). https://doi.org/10.1007/s12029-019-00204-1

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  • DOI: https://doi.org/10.1007/s12029-019-00204-1

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