Metachronous Hepatic Angiosarcoma Presenting as a Mimic of Recurrent Hepatocellular Carcinoma
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Primary hepatic angiosarcoma (PHA) is the third most common primary liver malignancy, after hepatocellular carcinoma and cholangiocarcinoma, accounting for 2% of primary liver malignancies and less than 1% of all sarcomas [1, 2]. PHA has been known to present in men over 60 years of age and has been associated with neurofibromatosis-1, anabolic steroids, hemochromatosis, vinyl chloride, thorotrast radiocontrast, and arsenic, although most cases are idiopathic [2, 3]. PHA is a very aggressive malignancy with a historical median survival of only 5 months despite treatment . Our case highlights how this deadly disease can present as a mimic of recurrent hepatocellular carcinoma (HCC) in a patient with known prior HCC.
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Conflict of Interest
The authors declare that they have no conflict of interest.